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颞下颌关节强直:采用全关节异体置换一期切除与重建的长期疗效——20年经验

Temporomandibular Joint Ankylosis: Long-Term Outcomes with One-Stage Resection and Reconstruction Using Total Joint Alloplastic Replacement-A 20-Year Experience.

作者信息

Gerbino Giovanni, Omedè Michela, Raveggi Elisa, Silvestri Sara, Zavattero Emanuele, Ramieri Guglielmo

机构信息

Division of Maxillofacial Surgery, Department of Surgical Sciences, University of Turin, Città della Salute e delle Scienze Hospital, Via Genova 3, 10131 Torino, Italy.

出版信息

J Clin Med. 2025 Jun 30;14(13):4639. doi: 10.3390/jcm14134639.

DOI:10.3390/jcm14134639
PMID:40649015
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12250143/
Abstract

Temporomandibular joint (TMJ) ankylosis, characterized by osseous-fibrous fusion, severely impairs mandibular function. While alloplastic total joint replacement (TJR) is the gold standard, long-term outcomes remain understudied. The aim of this study is to evaluate the long-term esthetic and functional outcomes of prosthetic replacement and to retrospectively analyze our 20-year experience. A retrospective observational study (2003-2024) was conducted at a tertiary referral center in Turin and enrolled patients who underwent alloplastic total joint replacement for TMJ ankylosis. Data collected included demographic variables, etiology, characteristics of the ankylosis, prosthesis type (stock/custom), surgical details, and outcomes (maximal interincisal opening [MIO], pain, quality of life, diet consistency, Helkimo index, complications). Among 28 patients (61% female, mean age 51.8 years), etiologies included post-traumatic (39%), osteoarthritis (32%), congenital (25%) and neoplastic (4%) causes. Custom prostheses were used in 57% of cases. Median follow-up was 11.5 years. Significant improvements were observed in MIO ( = 0.001), pain level ( = 0.001), quality of life ( = 0.001), diet score ( = 0.002), and Helkimo index ( = 0.001). Complications included facial nerve dysfunction (32.1%), salivary leakage (14.3%), and one recurrence (2.2%). Alloplstic TJR provides durable functional and esthetic restoration for TMJ ankylosis, with custom prostheses excelling in complex anatomies. Long-term stability (>10 years) supports its role as a definitive solution.

摘要

颞下颌关节(TMJ)强直以骨纤维融合为特征,严重损害下颌功能。虽然异体全关节置换术(TJR)是金标准,但长期疗效仍研究不足。本研究的目的是评估假体置换的长期美学和功能疗效,并回顾性分析我们20年的经验。在都灵的一家三级转诊中心进行了一项回顾性观察研究(2003 - 2024年),纳入了因TMJ强直接受异体全关节置换术的患者。收集的数据包括人口统计学变量、病因、强直的特征、假体类型(成品/定制)、手术细节以及疗效(最大切牙间开口度[MIO]、疼痛、生活质量、饮食稠度、赫尔基莫指数、并发症)。在28例患者中(61%为女性,平均年龄51.8岁),病因包括创伤后(39%)、骨关节炎(32%)、先天性(25%)和肿瘤性(4%)病因。57%的病例使用了定制假体。中位随访时间为11.5年。在MIO( = 0.001)、疼痛程度( = 0.001)、生活质量( = 0.001)、饮食评分( = 0.002)和赫尔基莫指数( = 0.001)方面观察到显著改善。并发症包括面神经功能障碍(32.1%)、唾液漏(14.3%)和1例复发(2.2%)。异体TJR为TMJ强直提供了持久的功能和美学恢复,定制假体在复杂解剖结构中表现出色。长期稳定性(>10年)支持其作为最终解决方案的作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/721a/12250143/4820bfd92a5e/jcm-14-04639-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/721a/12250143/86fe4a62bc50/jcm-14-04639-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/721a/12250143/6beea6c3f7ff/jcm-14-04639-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/721a/12250143/4dc9c59db60f/jcm-14-04639-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/721a/12250143/4820bfd92a5e/jcm-14-04639-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/721a/12250143/86fe4a62bc50/jcm-14-04639-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/721a/12250143/6beea6c3f7ff/jcm-14-04639-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/721a/12250143/4dc9c59db60f/jcm-14-04639-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/721a/12250143/4820bfd92a5e/jcm-14-04639-g004.jpg

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本文引用的文献

1
Defining Effect Size Standards in Temporomandibular Joint and Masticatory Muscle Research.颞下颌关节和咀嚼肌研究中效应量标准的定义
Med Sci Monit. 2025 May 1;31:e948365. doi: 10.12659/MSM.948365.
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Extended temporomandibular joint prostheses: a retrospective analysis of feasibility, outcomes, and complications.颞下颌关节延长假体:可行性、疗效及并发症的回顾性分析
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Quality of Life After Total Temporomandibular Joint Prothesis Surgery.全颞下颌关节置换术后的生活质量
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Temporomandibular joint ankylosis: A tertiary center-based epidemiological study.颞下颌关节强直:一项基于三级医疗中心的流行病学研究。
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Alloplastic total joint replacement in management of temporomandibular joint ankylosis.异质材料全关节置换术治疗颞下颌关节强直
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