Pelvic organ prolapse (POP) and urinary incontinence are prevalent conditions among women, significantly affecting their quality of life. Vaginal mesh surgeries, including the use of the Calistar mesh, have become an essential intervention aimed at alleviating symptoms associated with POP and urinary dysfunction. This study evaluates the clinical outcomes of Calistar vaginal mesh surgeries, focusing on pre- and post-operative changes in urinary parameters and prolapse severity. Data from 180 patients undergoing Calistar procedures were analyzed, revealing significant improvements in anatomical markers (Aa, Ba, C, Ap, and Bp) and urinary distress metrics (UDI-6 and IIQ-7) postoperatively. The results demonstrate that Calistar mesh procedures are effective in reducing urinary frequency, incontinence, and incomplete bladder emptying. Calistar mesh procedures offer a safe and effective surgical option for managing POP and associated urinary dysfunction. The observed anatomical and functional improvements suggest that Calistar mesh significantly enhances patient outcomes and quality of life.