Cavalcante Dos Santos Elaine, Demailly Zoé, Bakker Jan, Taccone Fabio Silvio
Department of Intensive Care, Erasme University Hospital, Université Libre de Bruxelles, Brussels, 1070, Belgium.
Medical Intensive Care Unit, CHU Rouen, Normandie Université, Rouen, F-76000, France.
J Clin Monit Comput. 2025 Jul 12. doi: 10.1007/s10877-025-01324-9.
Capillary refill time (CRT) is a vaso-occlusive test that allows the non-invasive assessment of skin perfusion. A vascular occlusive test (VOT) induces transient ischemia similar to that used in preconditioning ischemia. We hypothesized that CRT could be influenced by local tissue compression mimicking ischemic preconditioning when repeated measurements are performed. In healthy volunteers (n = 30), CRTs were performed twice on the index and middle fingers of the dominant hand and the index finger of the non-dominant hand at 15-minute intervals on the first day. On the second day, two CRT measurements were taken at 30-minute intervals. No significant differences were observed in CRT measurements repeated at 15- and 30-minute intervals. Additionally, baseline CRT values did not significantly differ between the fingers of the dominant and non-dominant hands on either study day. Repeated CRT measurements are not influenced by local ischemic preconditioning in the finger over short intervals.
毛细血管再充盈时间（CRT）是一种血管闭塞试验，可用于无创评估皮肤灌注情况。血管闭塞试验（VOT）会诱发类似于预处理缺血时的短暂性缺血。我们推测，当进行重复测量时，模拟缺血预处理的局部组织压迫可能会影响CRT。在30名健康志愿者中，第一天每隔15分钟在优势手的食指和中指以及非优势手的食指上进行两次CRT测量。第二天，每隔30分钟进行两次CRT测量。在15分钟和30分钟间隔重复进行的CRT测量中未观察到显著差异。此外，在任何一个研究日，优势手和非优势手手指的基线CRT值均无显著差异。短时间内，手指重复进行CRT测量不受局部缺血预处理的影响。
