Stéphan F, Réville P
MMW Munch Med Wochenschr. 1977 May 13;119(19):663-70.
The glucose tolerance of the normal woman is not disturbed by oral contraceptives, or only slightly so. In women with a hereditary diabetic taint or diabetic complications during pregnancy, however, the diabetogenic effect is intensified. Estrogens/gestagens (OE-P) are contraindicated in patients with latent diabetes because they may develop an irreversible manifest diabetes. OE-P may be given in manifest diabetes with careful supervision of the blood sugar, lipid levels and the vascular condition. The doses of insulin or oral antidiabetics must often be raised. If the diabetes is not adequately stabilized, the OE-P must be discontinued. Young diabetic women should have their children before the onset of vascular complications. If a diabetic has two living children, surgical sterilization must be given serious consideration.
正常女性的糖耐量不受口服避孕药影响，或仅有轻微影响。然而，对于有遗传性糖尿病倾向或孕期出现糖尿病并发症的女性，其致糖尿病作用会增强。雌激素/孕激素（口服避孕药）对潜伏性糖尿病患者是禁忌的，因为这类患者可能会发展为不可逆的显性糖尿病。口服避孕药可用于显性糖尿病患者，但需密切监测血糖、血脂水平及血管状况。通常必须增加胰岛素或口服降糖药的剂量。如果糖尿病病情未得到充分控制，必须停用口服避孕药。年轻的糖尿病女性应在血管并发症出现之前生育。如果糖尿病患者已有两个存活子女，则必须认真考虑手术绝育。
