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美国老年人在新冠疫情之前及期间带状疱疹疫苗接种率的变化。

Change in herpes zoster vaccination uptake before and during the COVID-19 pandemic in the United States older adults.

作者信息

Lin Jialing, Dai Zhaoli, Li Chenxi, He Wen-Qiang

机构信息

International Centre for Future Health Systems, University of New South Wales, Sydney, NSW 2052, Australia.

School of Population Health, University of New South Wales, Sydney, NSW 2052, Australia; UNSW Ageing Futures Institute, Faculty of Medicine and Health, University of New South Wales, Sydney, NSW 2052, Australia; School of Pharmacy, Faculty of Medicine and Health, The University of Sydney, Sydney, NSW 2006, Australia.

出版信息

Vaccine. 2025 Jul 12;62:127503. doi: 10.1016/j.vaccine.2025.127503.

Abstract

OBJECTIVES

To examine changes in herpes zoster (HZ) vaccination uptake among older adults in the United States before and during the COVID-19 pandemic and related factors.

METHODS

We estimated HZ vaccination uptake before (2018-2019) and during (2020-2022) the COVID-19 pandemic among adults aged ≥50 years using the National Health Interview Survey data. We used log-binomial regression to examine uptake changes with adjustment for and stratification by sociodemographic and health characteristics.

RESULTS

Among 79,786 adults (mean age: 66.4 years; male: 55.6 %), the uptake prevalence increased from 25.1 % before the pandemic to 30.1 % during the pandemic, with a 1.36-fold increase in prevalence (adjusted prevalence ratio: 1.36 [95 % CI: 1.30-1.41]). Such increase was observed across all subgroups, with more prominent increases among adults aged 50-64 years, men, non-Hispanic Black and other ethnicity, those with low household income, from West regions, living with partners, current smokers, received prior flu vaccinations, and those without comorbidities. Despite these increases, the uptake during the pandemic remained significantly lower in these subgroups compared to others.

CONCLUSIONS

Although HZ vaccination uptake among older adults increased during the COVID-19 pandemic compared to before the pandemic, and this increase was more prominent among ethnic minorities, low-income, and obese and smoker groups, uptake remains suboptimal. With the ageing population, ongoing monitoring and better strategies are required to ensure uptake continues to increase.

摘要

目的

研究美国老年人在2019冠状病毒病(COVID-19)大流行之前和期间带状疱疹(HZ)疫苗接种率的变化及相关因素。

方法

我们使用美国国家健康访谈调查数据,估计了年龄≥50岁的成年人在COVID-19大流行之前(2018 - 2019年)和期间(2020 - 2022年)的HZ疫苗接种率。我们使用对数二项回归分析,在对社会人口统计学和健康特征进行调整和分层的情况下,研究接种率的变化。

结果

在79,786名成年人中(平均年龄:66.4岁;男性:55.6%),接种率从大流行前的25.1%上升至大流行期间的30.1%,患病率增加了1.36倍(调整后的患病率比值:1.36 [95%置信区间:1.30 - 1.41])。在所有亚组中均观察到这种增加,在50 - 64岁的成年人、男性、非西班牙裔黑人及其他种族、家庭收入低、来自西部地区、与伴侣同住、当前吸烟者、之前接种过流感疫苗以及无合并症的人群中增加更为显著。尽管有这些增加,但与其他亚组相比,这些亚组在大流行期间的接种率仍然显著较低。

结论

尽管与大流行之前相比,COVID-19大流行期间老年人的HZ疫苗接种率有所增加,且这种增加在少数族裔、低收入、肥胖和吸烟者群体中更为突出,但接种率仍未达到最佳水平。随着人口老龄化,需要持续监测并制定更好的策略,以确保接种率持续上升。

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