Kaplan O, Skornick Y, Greif F, Klausner Y, Rozin R R
Eur J Surg Oncol. 1985 Dec;11(4):357-60.
Oestrogen receptor (OR) assay has an essential role in selecting therapy for breast cancer patients, OR status is probably also of prognostic value. The correlation between the size of the primary tumour and OR status was evaluated in 100 women with breast cancer. In 72 post-menopausal patients the OR average level was significantly higher in large primary tumours--T2, T3, when compared to OR levels of T1 tumours. In the 28 pre-menopausal women, this difference was not statistically significant. No correlation between OR level and stage of disease was found. Women presenting with large primary tumours do not necessarily have a poor prognosis.
雌激素受体（OR）检测在为乳腺癌患者选择治疗方案中起着至关重要的作用，OR状态可能也具有预后价值。对100例乳腺癌女性患者的原发肿瘤大小与OR状态之间的相关性进行了评估。在72例绝经后患者中，与T1期肿瘤的OR水平相比，T2、T3期大的原发肿瘤的OR平均水平显著更高。在28例绝经前女性中，这种差异无统计学意义。未发现OR水平与疾病分期之间存在相关性。原发肿瘤较大的女性患者预后不一定差。
