Combinatory Treatment to Alleviate Cellular Stress and Improve Skeletal Muscle Phenotype in Spinal Muscular Atrophy.
作者信息
Zeng Wenshu, Kong Xiaohui, Caudal Arianne, Zhao Shane Rui, Alamana Christina, Melesio Juan, Ren Lu, Guzman Jessica, Pang Paul D, Howell Kelly, Chen Karen S, Day John W, Wu Joseph C
机构信息
Stanford Cardiovascular Institute, Stanford University, CA. (W.Z., X.K., A.C., S.R.Z., C.A., J.M., L.R., J.C.W.).
Division of Cardiovascular Medicine, Department of Medicine, Stanford University, CA. (W.Z., X.K., A.C., S.R.Z., C.A., J.M., L.R., J.C.W.).
出版信息
Circ Res. 2025 Jul 14. doi: 10.1161/CIRCRESAHA.124.325931.
Abstract
摘要
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本文引用的文献
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Generation of two induced pluripotent stem cell lines from spinal muscular atrophy type 1 patients carrying no functional copies of SMN1 gene.从携带无功能 SMN1 基因拷贝的脊髓性肌萎缩症 1 型患者中生成两个诱导多能干细胞系。
Stem Cell Res. 2023 Jun;69:103095. doi: 10.1016/j.scr.2023.103095. Epub 2023 Apr 17.
2
Spinal muscular atrophy.脊髓性肌萎缩症。
Nat Rev Dis Primers. 2022 Aug 4;8(1):52. doi: 10.1038/s41572-022-00380-8.
3
Cannabinoid receptor 1 antagonist genistein attenuates marijuana-induced vascular inflammation.大麻素受体 1 拮抗剂染料木黄酮可减轻大麻引起的血管炎症。
Cell. 2022 May 12;185(10):1676-1693.e23. doi: 10.1016/j.cell.2022.04.005. Epub 2022 Apr 29.
4
Evaluation of the Isoflavone Genistein as Reversible Human Monoamine Oxidase-A and -B Inhibitor.异黄酮染料木黄酮作为可逆性人单胺氧化酶-A和-B抑制剂的评估。
Evid Based Complement Alternat Med. 2016;2016:1423052. doi: 10.1155/2016/1423052. Epub 2016 Mar 28.
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