Puglia Francesco, Ferraro Marcello, Longhi Valentina, Gallazzi Enrico, La Maida Giovanni Andrea
Specialized Unit of Pediatric Orthopedics and Traumatology, ASST Gaetano Pini/CTO, Milan, Italy.
Specialized Unit of Spinal Disorders and Scoliosis, ASST Gaetano Pini/CTO, Milan, Italy.
Orthop Res Rev. 2025 Jul 8;17:281-288. doi: 10.2147/ORR.S364680. eCollection 2025.
Spinal degenerative diseases are major contributors to chronic back pain and disability. Transforaminal lumbar interbody fusion (TLIF) is a widely used surgical approach to address these conditions by achieving vertebral fusion. The success of TLIF is significantly influenced by bone health, particularly bone mineral density (BMD), as low BMD increases risks of complications such as cage subsidence and pseudarthrosis. This systematic review evaluated factors predictive of TLIF outcomes, focusing on BMD, bone graft materials, and postoperative bone health monitoring. A comprehensive literature search was conducted according to PRISMA modalities, and ten studies met the inclusion criteria. This review emphasizes the importance of preoperative BMD assessment and tailored surgical strategies in optimizing TLIF outcomes. Future research should focus on defining BMD thresholds, developing innovative graft materials, and long-term studies to improve surgical success in TLIF procedures.
脊柱退行性疾病是导致慢性背痛和残疾的主要原因。经椎间孔腰椎椎体间融合术(TLIF)是一种广泛应用的手术方法,通过实现椎体融合来治疗这些疾病。TLIF的成功受骨健康状况的显著影响,尤其是骨矿物质密度(BMD),因为低骨密度会增加诸如椎间融合器下沉和假关节等并发症的风险。本系统评价评估了预测TLIF手术效果的因素,重点关注骨密度、骨移植材料和术后骨健康监测。根据PRISMA模式进行了全面的文献检索,有十项研究符合纳入标准。本综述强调了术前骨密度评估和量身定制的手术策略在优化TLIF手术效果方面的重要性。未来的研究应侧重于确定骨密度阈值、开发创新的移植材料,以及开展长期研究以提高TLIF手术的成功率。