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左冠状动脉异常起源于右肺动脉(ALCARPA):一例报告

Anomalous Origin of the Left Coronary Artery From the Right Pulmonary Artery (ALCARPA): A Case Report.

作者信息

Talwar Sachin, Sharma Srikant, Siddharth Bharat, Bhende Vishal V

机构信息

Cardiothoracic and Vascular Surgery, All India Institute of Medical Sciences, New Delhi, IND.

Cardiothoracic and Vascular Surgery, The Mission Hospital, Durgapur, IND.

出版信息

Cureus. 2025 Jul 12;17(7):e87762. doi: 10.7759/cureus.87762. eCollection 2025 Jul.

Abstract

Although the congenitally anomalous left coronary artery (LCA) is a rare condition, it can give rise to a most rare case, which is an anomalous LCA from the right pulmonary artery (RPA) (ALCARPA). If left untreated, ALCARPA results in myocardial territories receiving low-pressure, oxygen-poor blood. A male infant aged eight months exhibited signs of respiratory distress, poor feeding, and precordial activity. The diagnosis of ALCARPA is usually considered in infants with otherwise unexplained left ventricular dysfunction or mitral valve regurgitation. Imaging studies, including computed tomography angiography and echocardiography, showed a markedly dilated right coronary artery and a dilated left ventricle, confirming ALCARPA. Using autologous pericardium treated with glutaraldehyde, the abnormal LCA was directly anastomosed to the aorta. Postoperative recovery was uneventful, with elective inotropic support provided. To prevent fatal arrhythmias and myocardial ischemia, prompt diagnosis and surgical creation of a dual-coronary system are essential.

摘要

虽然先天性异常左冠状动脉(LCA)是一种罕见病症,但它可能引发一种极为罕见的情况,即起源于右肺动脉(RPA)的异常LCA(ALCARPA)。若不治疗,ALCARPA会导致心肌区域接受低压、缺氧血液。一名8个月大的男婴出现呼吸窘迫、喂养困难和心前区活动异常的症状。对于原因不明的左心室功能障碍或二尖瓣反流的婴儿,通常会考虑诊断为ALCARPA。包括计算机断层血管造影和超声心动图在内的影像学检查显示右冠状动脉明显扩张和左心室扩张,证实为ALCARPA。使用经戊二醛处理的自体心包,将异常的LCA直接与主动脉吻合。术后恢复顺利,并提供了选择性的正性肌力支持。为预防致命性心律失常和心肌缺血,及时诊断并手术建立双冠状动脉系统至关重要。

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