Bohidar Pooja, Debta Fakir M, Das Suryakanta, Agarwal Kunal, Mishra Ekagrata, Krishnapriya Balappa D S J
Department of Oral Medicine and Radiology, S.C.B Govt. Dental College and Hospital, Cuttack, Odisha, India.
Department of Orthodontics and Dentofacial Orthopaedics, S.C.B Govt. Dental College and Hospital, Cuttack, Odisha, India.
J Pharm Bioallied Sci. 2025 Jun;17(Suppl 2):S1607-S1609. doi: 10.4103/jpbs.jpbs_176_25. Epub 2025 Jun 18.
Oral Submucous Fibrosis (OSMF) is slowly progressing chronic mucosal disease that can affect any part of the oral mucosa, even the pharynx. The soft palate and uvula also undergo significant fibrosis.
A total number of 200 patients (study and control groups with 100 participants each), were evaluated clinically for OSMF. The velar morphology was studied using digital Lateral Cephalogram.
Data were evaluated in SPSS with Chi square test, the independent -test and one way ANOVA.
In the 100 cases and 100 controls, the age ranged between 17 and 72 years. In the study group, 11 (11%) participants revealed Stage I OSMF,36 (36%) participants presented with Stage II OSMF, and rest 53 (53%) had Stage III OSMF. Mean velar length in Stage I was 3.42 cm, in Stage II it was 3.15 cm and in Stage III it was 3.022 cm. Similarly, the mean pharyngeal depth, velum angle and need's ratio also increased as staging of OSMF progressed. Mean velar width in Stage I was 1.00 cm, in Stage II it was 0.92 cm and in Stage III it was 0.94 cm. Mean distribution of velar length, need's ratio among stages of OSMF showed statistically significant result with value of less than 0.05.
This present study revealed that the soft palate changes its form to short and bulky in OSMF patients.
口腔黏膜下纤维化（OSMF）是一种进展缓慢的慢性黏膜疾病，可累及口腔黏膜的任何部位，甚至咽部。软腭和悬雍垂也会发生显著纤维化。
共有200名患者（研究组和对照组各100名参与者）接受了OSMF的临床评估。使用数字化侧位头影测量片研究腭部形态。
数据在SPSS中采用卡方检验、独立样本t检验和单因素方差分析进行评估。
在100例病例和100例对照中，年龄在17至72岁之间。在研究组中，11名（11%）参与者为I期OSMF，36名（36%）参与者为II期OSMF，其余53名（53%）为III期OSMF。I期腭部平均长度为3.42厘米，II期为3.15厘米，III期为3.022厘米。同样，随着OSMF分期的进展，平均咽深度、腭帆角和需求比也增加。I期腭部平均宽度为1.00厘米，II期为0.92厘米，III期为0.94厘米。OSMF各阶段腭部长度、需求比的平均分布显示，p值小于0.05，具有统计学意义。
本研究表明，OSMF患者的软腭形态会变为短而粗大。
