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原位肝移植术后胆泥综合征1例罕见病例

A Rare Case of Biliary Cast Syndrome After Orthotopic Liver Transplantation.

作者信息

Refaey Abdelrhman, Attia Ahmed, Ebeid Ahmed, Gray Stephen, Abutaleb Ameer

机构信息

Internal Medicine, Transplant Institute, George Washington University School of Medicine and Health Sciences, Washington DC, USA.

Internal Medicine, Holy Name Medical Center, Teaneck NJ, USA.

出版信息

Cureus. 2025 Jun 12;17(6):e85883. doi: 10.7759/cureus.85883. eCollection 2025 Jun.

DOI:10.7759/cureus.85883
PMID:40656370
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12255848/
Abstract

Biliary cast syndrome (BCS) is a rare complication following orthotopic liver transplantation (OLT), characterized by the formation of casts within the biliary system. We present the case of a 48-year-old woman who developed BCS nine weeks post-transplant. The patient experienced multiple complications, including biloma formation, recurrent anemia, and septic shock. Endoscopic retrograde cholangiopancreatography (ERCP) revealed extensive biliary casts, which were partially removed using a SpyBite basket (Boston Scientific, Marlborough, MA, USA). This case highlights a rare but serious complication of liver transplantation. Early recognition and aggressive treatment are crucial for improving outcomes in liver transplant recipients with BCS.

摘要

胆泥综合征(BCS)是原位肝移植(OLT)后一种罕见的并发症,其特征是在胆道系统内形成胆泥。我们报告一例48岁女性患者,在移植后9周发生了BCS。该患者出现了多种并发症,包括胆汁瘤形成、复发性贫血和感染性休克。内镜逆行胰胆管造影(ERCP)显示广泛的胆泥,使用SpyBite网篮(美国马萨诸塞州马尔伯勒市波士顿科学公司)部分取出。本病例突出了肝移植一种罕见但严重的并发症。早期识别和积极治疗对于改善BCS肝移植受者的预后至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3bd7/12255848/608a8cdd8723/cureus-0017-00000085883-i06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3bd7/12255848/8318b90db9fa/cureus-0017-00000085883-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3bd7/12255848/2fa4e197a07b/cureus-0017-00000085883-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3bd7/12255848/8711073ebc7a/cureus-0017-00000085883-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3bd7/12255848/efd1bded2404/cureus-0017-00000085883-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3bd7/12255848/1e624226697b/cureus-0017-00000085883-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3bd7/12255848/608a8cdd8723/cureus-0017-00000085883-i06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3bd7/12255848/8318b90db9fa/cureus-0017-00000085883-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3bd7/12255848/2fa4e197a07b/cureus-0017-00000085883-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3bd7/12255848/8711073ebc7a/cureus-0017-00000085883-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3bd7/12255848/efd1bded2404/cureus-0017-00000085883-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3bd7/12255848/1e624226697b/cureus-0017-00000085883-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3bd7/12255848/608a8cdd8723/cureus-0017-00000085883-i06.jpg

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本文引用的文献

1
Biliary cast syndrome post-liver transplantation: risk factors and outcome.肝移植术后胆砂综合征:危险因素和结局。
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Bile duct stones and casts after liver transplantation: Different entities but similar prevention strategy?肝移植术后胆管结石与胆管铸型:不同的实体但预防策略相似?
Liver Transpl. 2008 Oct;14(10):1400-3. doi: 10.1002/lt.21628.
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Biliary cast syndrome following liver transplantation: Predictive factors and clinical outcomes.肝移植术后胆管铸型综合征:预测因素及临床结局
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