Dewi Made Ratna, Lauren Christopher, Wahyudana I Nyoman Gde, Analysa Analysa, Wibawa Ida Bagus Gede Adiguna, Kencana I Gusti Ketut Agung Surya, Mahadewa Tjokorda Gde Bagus
Neurosurgery Division, Department of Surgery, Tabanan General Hospital, Tabanan, Indonesia.
Neurosurgery Division, Department of Surgery, Faculty of Medicine, Udayana University, Ngoerah Hospital, Denpasar, Indonesia.
Surg Neurol Int. 2025 Jun 20;16:254. doi: 10.25259/SNI_289_2025. eCollection 2025.
Parosteal lipomas are rare benign soft-tissue tumors that develop in close association with the periosteum. Skull involvement is exceptionally uncommon, with only a few cases reported in the literature.
A 14-year-old female presented with a slowly enlarging, painless lump above her right ear, first noticed at the age of five. Physical examination revealed a firm, well-defined, immobile mass measuring 2.5 × 1.5 cm in the supra-auricular region. A non-contrast computed tomography scan demonstrated a hypodense mass with thickening of the underlying squamous and mastoid bones, along with mastoid air cell enlargement. Surgical excision was performed for cosmetic reasons and histopathological diagnosis. Intraoperatively, the mass was found to be adherent to the periosteum and underlying bone. Histopathological examination confirmed the diagnosis of parosteal lipoma, showing mature adipose tissue, fibrous tissue, and focal lymphocytic aggregates without signs of malignancy. The patient recovered well postoperatively, with no recurrence or complications over 6 months of follow-up.
Parosteal lipomas of the skull are exceedingly rare and require clinical suspicion for diagnosis. Imaging aids in preoperative planning, while histopathological assessment confirms the diagnosis. Complete surgical excision is curative, with a favorable prognosis. This case adds to the limited literature on skull-based parosteal lipomas.
骨旁脂肪瘤是罕见的良性软组织肿瘤,与骨膜紧密相关。颅骨受累极为罕见,文献中仅报道了少数病例。
一名14岁女性患者,右耳上方有一个缓慢增大的无痛肿块,5岁时首次发现。体格检查发现耳上区域有一个质地坚硬、边界清晰、固定不动的肿块,大小为2.5×1.5厘米。非增强计算机断层扫描显示一个低密度肿块,其下方的鳞状骨和乳突骨增厚,同时乳突气房扩大。出于美容原因和组织病理学诊断进行了手术切除。术中发现肿块与骨膜和下方的骨质粘连。组织病理学检查证实为骨旁脂肪瘤,显示为成熟的脂肪组织、纤维组织和局灶性淋巴细胞聚集,无恶性迹象。患者术后恢复良好,随访6个月无复发或并发症。
颅骨骨旁脂肪瘤极为罕见,诊断需要临床怀疑。影像学有助于术前规划,而组织病理学评估可确诊。完整的手术切除可治愈,预后良好。该病例补充了关于颅骨骨旁脂肪瘤的有限文献。