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High HLA Sensitization After Early Renal Allograft Vascular Thrombosis.

作者信息

Pérez-Sáez María José, Comas Jordi, Melilli Edoardo, Moreso Francesc, Guirado Lluis, Vila Anna, Diekmann Fritz, Palou Eduard, Tort Jaume, Redondo-Pachón Dolores, Crespo Marta

机构信息

Nephrology Department, Hospital del Mar, RICORS2040 RD21/0005/0022, Barcelona, Spain.

Hospital del Mar Research Institute, Barcelona, Spain.

出版信息

Transpl Int. 2025 Jun 27;38:14457. doi: 10.3389/ti.2025.14457. eCollection 2025.

DOI:10.3389/ti.2025.14457
PMID:40656559
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12245732/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2d4c/12245732/148a781ce6cf/ti-38-14457-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2d4c/12245732/148a781ce6cf/ti-38-14457-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2d4c/12245732/148a781ce6cf/ti-38-14457-g001.jpg

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1
High HLA Sensitization After Early Renal Allograft Vascular Thrombosis.早期肾移植血管血栓形成后高HLA致敏
Transpl Int. 2025 Jun 27;38:14457. doi: 10.3389/ti.2025.14457. eCollection 2025.
2
Independent of nephrectomy, weaning immunosuppression leads to late sensitization after kidney transplant failure.独立于肾切除术，免疫抑制药物的逐渐撤用会导致移植肾失功后的晚期致敏。
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Harmful effect of preformed anti-MICA antibodies on renal allograft evolution in early posttransplantation period.移植后早期预存抗-MICA 抗体对肾移植的不良影响。
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Anti-HLA Antibodies After Precocious Transplantectomy by Vascular Thrombosis.
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HLA phenotypes of ESRD patients are risk factors in the panel-reactive antibody (PRA) response.终末期肾病（ESRD）患者的人类白细胞抗原（HLA）表型是群体反应性抗体（PRA）反应中的危险因素。
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本文引用的文献

1
Evolution of kidney allograft loss causes over 40 years (1979-2019).40多年来（1979年至2019年）肾移植受者失肾原因的演变
Nefrologia (Engl Ed). 2023 May-Jun;43(3):316-327. doi: 10.1016/j.nefroe.2023.07.003. Epub 2023 Jul 26.
2
Challenges in the management of the kidney allograft: from decline to failure: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference.移植肾管理面临的挑战：从下降到衰竭：KDIGO 争议会议的结论。
Kidney Int. 2023 Dec;104(6):1076-1091. doi: 10.1016/j.kint.2023.05.010. Epub 2023 May 24.
3
Rapid re-transplantation safety following early kidney graft loss.
早期移植肾丢失后快速再次移植的安全性。
Nephrology (Carlton). 2021 Sep;26(9):742-747. doi: 10.1111/nep.13907. Epub 2021 Jun 5.
4
The mode of sensitization and its influence on allograft outcomes in highly sensitized kidney transplant recipients.高度致敏的肾移植受者致敏方式及其对同种异体移植物结局的影响。
Nephrol Dial Transplant. 2016 Oct;31(10):1746-53. doi: 10.1093/ndt/gfw099. Epub 2016 Jul 6.
5
Early graft loss after kidney transplantation: risk factors and consequences.肾移植后早期移植物失功：危险因素和后果。
Am J Transplant. 2015 Jun;15(6):1632-43. doi: 10.1111/ajt.13162. Epub 2015 Feb 23.
6
Donor-specific antibodies after ceasing immunosuppressive therapy, with or without an allograft nephrectomy.停止免疫抑制治疗后，有无同种异体移植物肾切除术的供体特异性抗体。
Clin J Am Soc Nephrol. 2012 Aug;7(8):1310-9. doi: 10.2215/CJN.00260112. Epub 2012 May 24.