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病例报告:主动脉内球囊反搏用于一名难治性心源性休克合并严重主动脉瓣狭窄的患者——低主动脉顺应性增强血流动力学反应

Case Report: Intra-aortic balloon pump in a patient with refractory cardiogenic shock complicating severe aortic stenosis-enhanced hemodynamic response with low aortic compliance.

作者信息

Ota Issei, Sawada Kenichiro, Saku Keita, Noguchi Teruo

机构信息

Division of Cardiovascular Intensive Care, Department of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, Suita, Osaka, Japan.

Department of Cardiovascular Dynamics, National Cerebral and Cardiovascular Center, Suita, Osaka, Japan.

出版信息

Front Cardiovasc Med. 2025 Jun 27;12:1587383. doi: 10.3389/fcvm.2025.1587383. eCollection 2025.

Abstract

Intra-aortic balloon pump (IABP) counterpulsation generates pressure changes that are primarily influenced by aortic compliance, an index of arterial elasticity that varies widely among patients with cardiovascular disease. However, the potential role of aortic compliance in determining IABP efficacy remains poorly understood. We present the case of an 80-year-old man with severe aortic stenosis and pneumonia who was admitted with generalized fatigue and worsening dyspnea. He developed refractory Society for Cardiovascular Angiography & Interventions stage D cardiogenic shock despite multiple vasopressors. In this patient, who had low aortic compliance (0.62-0.81 ml/mmHg), IABP initiation resulted in immediate hemodynamic improvement through enhanced diastolic augmentation and systolic unloading, leading to rapid reversal of both hypoperfusion and pulmonary congestion. Following successful weaning from vasopressors and IABP removal, the patient underwent transcatheter aortic valve replacement without temporary mechanical circulatory support-related complications. The notable hemodynamic improvement observed in this case highlights the potential importance of aortic compliance as a key determinant of IABP efficacy in elderly patients with cardiogenic shock, suggesting that aortic compliance may help optimize patient selection for IABP support.

摘要

主动脉内球囊反搏(IABP)产生的压力变化主要受主动脉顺应性影响,主动脉顺应性是动脉弹性的指标,在心血管疾病患者中差异很大。然而,主动脉顺应性在确定IABP疗效方面的潜在作用仍知之甚少。我们报告一例80岁男性患者,患有严重主动脉瓣狭窄和肺炎,因全身疲劳和呼吸困难加重入院。尽管使用了多种血管升压药,他仍发展为难治性心血管造影和介入学会D期心源性休克。在这名主动脉顺应性较低(0.62 - 0.81 ml/mmHg)的患者中,启动IABP通过增强舒张期增压和收缩期减负立即改善了血流动力学,导致灌注不足和肺淤血迅速逆转。在成功停用血管升压药并移除IABP后,患者接受了经导管主动脉瓣置换术,未出现与临时机械循环支持相关的并发症。该病例中观察到的显著血流动力学改善突出了主动脉顺应性作为老年心源性休克患者IABP疗效关键决定因素的潜在重要性,表明主动脉顺应性可能有助于优化IABP支持的患者选择。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4dde/12245855/5158597f98d6/fcvm-12-1587383-g001.jpg

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