Martini A K
Handchir Mikrochir Plast Chir. 1985 Sep;17(5):266-9.
Animal experiments were performed in an attempt to prevent formation of amputation neuromas. For this purpose lyophilized homologous nerve transplants were used. Experiments were performed with the sciatic nerve of the rat. Results were compared with those achieved by using fresh autologous transplants and by covering the nerve ends with fibrin glue. Axons exhibited reduced growth within the empty spaces of the lyophilized transplant thus limiting uncontrolled growth of axons. Neuromas never occurred at the free end of this lyophilized transplant. Neuromas observed (13 out of 90) occurred at the juncture site. With respect to suture techniques epineural suture in combination with fibrin glue proved to be best.
为了防止截肢神经瘤的形成进行了动物实验。为此使用了冻干的同种异体神经移植。实验采用大鼠坐骨神经进行。将结果与使用新鲜自体移植以及用纤维蛋白胶覆盖神经末端所取得的结果进行比较。轴突在冻干移植物的空隙内生长减少，从而限制了轴突的无控制生长。在这种冻干移植物的游离端从未发生过神经瘤。观察到的神经瘤（90例中有13例）发生在缝合部位。就缝合技术而言，神经外膜缝合结合纤维蛋白胶被证明是最佳的。
