Otake Ryo, Mizutani Kazuki, Horita Ryo, Kaneko Umihiko, Hachinohe Daisuke
Department of Cardiology, Asia Medical Group, Sapporo Heart Center, Sapporo Cardio Vascular Clinic, North 49, East 16, 8-1, Higashi Ward, Sapporo, Hokkaido 007-0849, Japan.
Eur Heart J Case Rep. 2025 Jun 30;9(7):ytaf315. doi: 10.1093/ehjcr/ytaf315. eCollection 2025 Jul.
The number of transcatheter aortic valve implantation (TAVI) procedures has increased significantly and now includes younger and higher-risk surgical patients. As early-generation transcatheter heart valves (THVs) continue to degrade over time, the incidence of structural valve deterioration (SVD) is increasing, requiring more complex valve-in-valve (TAV-in-TAV) procedures.
We present a case of SVD of a THV, resulting in severe aortic regurgitation in an 88-year-old female with decompensated heart failure. Eight years prior, the patient had undergone TAVI with SAPIEN XT 23 mm via the transapical approach because of severe calcified stenosis of the lower extremity arteries and extreme tortuosity from the arch to the descending aorta and abdominal aortic aneurysm, right-sided aortic arch. Considering the patient's condition and access route, we performed emergency transfemoral TAV-in-TAV using a 23 mm SAPIEN3 Ultra RESILIA. The endoconduit technique successfully facilitated sheath passage. The valve was implanted without complications. The procedure was successful, resulting in only trace paravalvular regurgitation. The post-operative effective orifice area was 1.80 cm² (indexed EOA: 1.32 cm²/m²). The Doppler Velocity Index was 0.59, suggesting no significant patient-prosthesis mismatch.
Vascular anomalies often restrict the choice of a safe access route in TAVI procedures. The endoconduit technique provides a minimally invasive solution for accessing complex iliac arteries. This case illustrates the importance of selecting the appropriate sheath, utilising endoconduit, and employing various procedural techniques to manage complex anatomies and ensure successful outcomes in TAV-in-TAV procedures.
经导管主动脉瓣植入术(TAVI)的手术数量显著增加,目前纳入了更年轻且手术风险更高的患者。随着早期一代经导管心脏瓣膜(THV)随时间推移持续退化,结构性瓣膜衰败(SVD)的发生率不断上升,需要更复杂的瓣中瓣(TAV-in-TAV)手术。
我们报告一例THV发生SVD的病例,该病例导致一名88岁失代偿性心力衰竭女性出现严重主动脉瓣反流。八年前,由于下肢动脉严重钙化狭窄以及从主动脉弓到降主动脉和腹主动脉瘤、右侧主动脉弓极度迂曲,该患者经心尖途径接受了使用23mm SAPIEN XT的TAVI。考虑到患者的病情和入路途径,我们使用23mm SAPIEN3 Ultra RESILIA经股动脉紧急实施了TAV-in-TAV。内导管技术成功促进了鞘管通过。瓣膜植入无并发症。手术成功,仅出现微量瓣周反流。术后有效瓣口面积为1.80cm²(指数化EOA:1.32cm²/m²)。多普勒速度指数为0.59,提示无明显的人工瓣膜-患者不匹配。
血管异常常常限制TAVI手术中安全入路途径的选择。内导管技术为进入复杂的髂动脉提供了一种微创解决方案。本病例说明了在TAV-in-TAV手术中选择合适的鞘管、利用内导管以及采用各种手术技术来处理复杂解剖结构并确保成功结果的重要性。