Bashar Noorul, Kundu Bidyut Kumar, Han Guanqun, Garcia Santana P, Krause Jeanette A, Turro Claudia, Sun Yujie
Department of Chemistry, University of Cincinnati, Cincinnati, Ohio 45221, United States.
Department of Chemistry and Biochemistry, The Ohio State University, Columbus, Ohio 43210, United States.
Inorg Chem. 2025 Jul 28;64(29):14810-14816. doi: 10.1021/acs.inorgchem.5c00853. Epub 2025 Jul 14.
The advancement of metallaphotoredox catalysis in organic synthesis largely relies on the development of competent photosensitizers and additional organic ligands stabilizing metal cocatalysts. To simplify the complex and costly metallaphotoredox systems, we hereby introduce 2,2'-bibenzothiazole (dBZ), an organic chromophore exhibiting unprecedented dual functionality in organic photocatalysis. A series of photophysical, electrochemical, and photocatalytic studies demonstrated the competence of dBZ in driving various organic transformations as a sole photocatalyst. More importantly, when coupled with nickel acetate, dBZ was able to perform many challenging C-C and C-N coupling reactions in the absence of additional organic ligands, marking a departure from conventional metallaphotoredox strategies and highlighting its unique role in streamlining photocatalytic protocols. In short, the dual functionality of dBZ not only simplifies the photocatalytic system but also reduces the overall cost, representing an innovative direction in organic photocatalysis.
金属光氧化还原催化在有机合成中的进展很大程度上依赖于高效光敏剂的开发以及稳定金属助催化剂的其他有机配体。为了简化复杂且昂贵的金属光氧化还原体系，我们在此引入2,2'-联苯并噻唑（dBZ），一种在有机光催化中展现出前所未有的双重功能的有机发色团。一系列光物理、电化学和光催化研究证明了dBZ作为单一光催化剂驱动各种有机转化的能力。更重要的是，当与乙酸镍结合时，dBZ能够在没有额外有机配体的情况下进行许多具有挑战性的C-C和C-N偶联反应，这与传统的金属光氧化还原策略不同，并突出了其在简化光催化方案中的独特作用。简而言之，dBZ的双重功能不仅简化了光催化体系，还降低了总成本，代表了有机光催化的一个创新方向。
