早期乳腺癌的术中放射治疗：希望还是风险？ - Suppr

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Intraoperative Radiation Therapy for Early-Stage Breast Cancer: Promise or Peril?

作者信息

Vicini Frank A

机构信息

Michigan Healthcare Professionals, Farmington Hills, MI, USA.

出版信息

Ann Surg Oncol. 2025 Jul 14. doi: 10.1245/s10434-025-17785-w.

DOI:10.1245/s10434-025-17785-w

PMID:40659889

Abstract

摘要

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Intraoperative Radiation Therapy for Early-Stage Breast Cancer: Promise or Peril?早期乳腺癌的术中放射治疗：希望还是风险？

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本文引用的文献

Single-modality endocrine therapy versus radiotherapy after breast-conserving surgery in women aged 70 years and older with luminal A-like early breast cancer (EUROPA): a preplanned interim analysis of a phase 3, non-inferiority, randomised trial.70岁及以上患有腔面A型早期乳腺癌女性保乳术后单模态内分泌治疗与放疗的比较（EUROPA）：一项3期非劣效性随机试验的预先计划中期分析

Lancet Oncol. 2025 Jan;26(1):37-50. doi: 10.1016/S1470-2045(24)00661-2. Epub 2024 Dec 12.

Reimagining Deintensification for Low-Risk Breast Cancer.重新构想低风险乳腺癌的降阶梯治疗

JCO Oncol Pract. 2025 Mar;21(3):323-332. doi: 10.1200/OP-24-00538. Epub 2024 Oct 15.

Partial Breast Irradiation for Patients With Early-Stage Invasive Breast Cancer or Ductal Carcinoma In Situ: An ASTRO Clinical Practice Guideline.早期浸润性乳腺癌或导管原位癌患者的部分乳腺照射：美国放射肿瘤学会临床实践指南

Pract Radiat Oncol. 2024 Mar-Apr;14(2):112-132. doi: 10.1016/j.prro.2023.11.001. Epub 2023 Nov 15.

Accelerated Partial Breast Irradiation Using External Beam or Intraoperative Electron Radiation Therapy: 5-Year Oncological Outcomes of a Prospective Cohort Study.采用外照射或术中电子放射治疗加速部分乳房照射：一项前瞻性队列研究的 5 年肿瘤学结果。

Int J Radiat Oncol Biol Phys. 2022 Jul 1;113(3):570-581. doi: 10.1016/j.ijrobp.2022.03.010. Epub 2022 Mar 15.

An Estimate of Local Failure in the TARGIT-A Trial of Pre-pathology Intraoperative Radiation Therapy for Early Breast Cancer.早期乳腺癌术前经皮内放射治疗 TARGIT-A 试验中局部失败的估计。

Int J Radiat Oncol Biol Phys. 2023 Jan 1;115(1):73-76. doi: 10.1016/j.ijrobp.2021.12.161. Epub 2022 Jan 20.

Delivery of Adjuvant Radiation in 5 Days or Less After Lumpectomy for Breast Cancer: A Systematic Review.乳腺癌保乳术后5天或更短时间内进行辅助放疗：一项系统评价

Int J Radiat Oncol Biol Phys. 2022 Apr 1;112(5):1090-1104. doi: 10.1016/j.ijrobp.2021.11.026. Epub 2021 Dec 16.

Intraoperative irradiation for early breast cancer (ELIOT): long-term recurrence and survival outcomes from a single-centre, randomised, phase 3 equivalence trial.早期乳腺癌术中放疗（ELIOT）：来自单中心、随机、3 期等效性试验的长期复发和生存结果。

Lancet Oncol. 2021 May;22(5):597-608. doi: 10.1016/S1470-2045(21)00080-2. Epub 2021 Apr 9.

TARGIT-R (Retrospective): 5-Year Follow-Up Evaluation of Intraoperative Radiation Therapy (IORT) for Breast Cancer Performed in North America.TARGIT-R（回顾性研究）：北美地区乳腺癌术中放疗（IORT）的5年随访评估

Ann Surg Oncol. 2021 May;28(5):2512-2521. doi: 10.1245/s10434-020-09432-3. Epub 2021 Jan 12.

Accelerated Partial-Breast Irradiation Compared With Whole-Breast Irradiation for Early Breast Cancer: Long-Term Results of the Randomized Phase III APBI-IMRT-Florence Trial.加速部分乳房照射与全乳房照射治疗早期乳腺癌的比较：APBI-IMRT-Florence 随机 III 期试验的长期结果。

J Clin Oncol. 2020 Dec 10;38(35):4175-4183. doi: 10.1200/JCO.20.00650. Epub 2020 Aug 24.

Long term survival and local control outcomes from single dose targeted intraoperative radiotherapy during lumpectomy (TARGIT-IORT) for early breast cancer: TARGIT-A randomised clinical trial.保乳术后单次剂量靶向术中放疗（TARGIT-IORT）治疗早期乳腺癌的长期生存和局部控制结果：TARGIT-A 随机临床试验。

BMJ. 2020 Aug 19;370:m2836. doi: 10.1136/bmj.m2836.

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