Shen Yun, Hu Gang
Pennington Biomedical Research Center, Baton Rouge, Louisiana, USA.
Obesity (Silver Spring). 2025 Jul 14. doi: 10.1002/oby.24352.
We aimed to estimate the prevalence of clinical obesity among US adults using the newly proposed definition and evaluate differences across demographic subgroups.
This cross-sectional study analyzed data from the National Health and Nutrition Examination Survey (NHANES) 2017-2020 cycle. The analysis included 8037 adults aged 20 years or older with complete data. Clinical obesity was defined per the Lancet Diabetes & Endocrinology Commission on the definition and diagnosis of clinical obesity.
Among 8037 participants, the overall prevalence of clinical obesity was 9.7% (95% CI, 8.9%-10.5%), with comparable prevalence in males (9.8%) and in females (9.6%). Younger adults (aged 20-39 years) exhibited the highest prevalence (11.9%), followed by those aged 40-59 years (8.2%). Significant racial/ethnic and sex disparities were observed, with Mexican females having the highest prevalence (13.9%), followed by non-Hispanic Black females (13.5%) and non-Hispanic White males (10.6%). The prevalence decreased significantly when the new definition with organ dysfunctions or limitations of daily activities was applied compared with BMI alone.
This study provided the first nationally representative estimates of clinical obesity prevalence in US adults based on the new definition.
我们旨在使用新提出的定义估算美国成年人临床肥胖的患病率,并评估不同人口亚组之间的差异。
这项横断面研究分析了2017 - 2020年国家健康与营养检查调查(NHANES)的数据。分析纳入了8037名20岁及以上且数据完整的成年人。临床肥胖是根据《柳叶刀·糖尿病与内分泌学》临床肥胖定义与诊断委员会的定义来界定的。
在8037名参与者中,临床肥胖的总体患病率为9.7%(95%置信区间,8.9% - 10.5%),男性患病率(9.8%)与女性患病率(9.6%)相当。较年轻的成年人(20 - 39岁)患病率最高(11.9%),其次是40 - 59岁的成年人(8.2%)。观察到显著的种族/族裔和性别差异,墨西哥裔女性患病率最高(13.9%),其次是非西班牙裔黑人女性(13.5%)和非西班牙裔白人男性(10.6%)。与仅使用体重指数(BMI)相比,应用包含器官功能障碍或日常活动受限的新定义时,患病率显著降低。
本研究基于新定义首次提供了美国成年人临床肥胖患病率的全国代表性估计值。