Dal Negro R W, Turco P, Zoccatelli O, Pomari C, Trevisan F
Int J Clin Pharmacol Res. 1985;5(5):345-50.
Sixty-five patients, 25 with acute bronchopulmonary respiratory tract diseases and 40 with acute exacerbations of chronic respiratory tract infections, were treated by means of intramuscular injection of an extempore combination of 1 g of cefuroxime and 300 mg of acetylcysteine. Patients were divided into two groups according to the acute or chronic nature of their respiratory tract diseases. Positive clinical results were obtained in 62 of the 65 patients. Of a total of 52 pathogens isolated in pretreatment bacteriological tests on sputum cultures, only three were still detectable after treatment. Tolerance of the treatment was good in all patients, no side-effects of any kind being observed.
65例患者接受了治疗，其中25例患有急性支气管肺部呼吸道疾病，40例患有慢性呼吸道感染急性加重。治疗方法为肌肉注射1克头孢呋辛和300毫克乙酰半胱氨酸的临时组合。根据呼吸道疾病的急性或慢性性质将患者分为两组。65例患者中有62例取得了阳性临床结果。在治疗前对痰培养进行的细菌学检测中分离出的总共52种病原体中，治疗后仅检测到3种。所有患者对治疗的耐受性良好，未观察到任何类型的副作用。
