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比较Park表增强剂量与标准手术剂量在急性后天性共同性内斜视中的应用:一项回顾性分析。

Comparing Park Table - Augmented and Standard Surgical Doses in Acute Acquired Comitant Esotropia: A Retrospective Analysis.

作者信息

Srimanan Worapot

机构信息

Division of Ophthalmology, Phramongkutklao Hospital, Bangkok, Thailand.

出版信息

Clin Ophthalmol. 2025 Jul 10;19:2211-2220. doi: 10.2147/OPTH.S530750. eCollection 2025.

Abstract

PURPOSE

Acquired comitant esotropia (ACE) is a rare condition characterized by the sudden onset of inward eye deviation. In non-recovered cases, surgery was performed. The standard surgical dose typically leads to undercorrection, and multimodal approaches were used to enhance outcomes. The current study aimed to explore the clinical course and identify factors influencing surgical success in patients with ACE at a tertiary hospital.

PATIENTS AND METHODS

This retrospective study reviewed the electronic medical records of 99 patients diagnosed with ACE at Phramongkutklao Hospital between 2014 and 2024. Data collected included patient demographics, underlying etiologies, clinical presentations, treatment approaches, and surgical outcomes. Surgical cases were categorized based on the use of either the standard Park surgical dosage or an augmented dose, defined as an additional 0.5 mm beyond the standard amount. Factors associated with successful surgical outcomes were also evaluated through statistical analysis.

RESULTS

The mean age at diagnosis was 28.97 ± 19.67 years, with a slight predominance of men. ACE was classified as types I (Swan type), II (Burian-Franceschetti), and III (Bielschowsky) in 8.08% (8/99), 46.46% (46/99), and 45.45% (45/99), respectively. All cases were idiopathic, with neuroimaging abnormalities detected in 4.04% (4/99) of patients. Surgical intervention was required in 79.8% (79/99) of cases. One year postoperatively, 75% (54/72) of patients demonstrated substantial improvement in ocular alignment. Based on subgroup analysis, the success rate was 91.18% in the augmented group and 60.53% in the non-augmented group. Logistic regression analysis indicated that an augmented surgical dose was significantly associated with favorable surgical outcomes (adjusted odds ratio: 5.50; 95% confidence interval [95% CI], 1.32-22.89).

CONCLUSION

This study demonstrates a high surgical success rate in patients with ACE, supporting the potential use of augmented surgical doses. Further research is warranted to identify additional prognostic factors and refine treatment strategies for optimal ACE management.

摘要

目的

获得性共同性内斜视(ACE)是一种罕见疾病,其特征为突然出现眼球向内偏斜。在未恢复的病例中,进行了手术。标准手术剂量通常导致矫正不足,因此采用多模式方法来提高治疗效果。本研究旨在探讨三级医院中ACE患者的临床病程,并确定影响手术成功的因素。

患者与方法

这项回顾性研究回顾了2014年至2024年间在佛统府医院诊断为ACE的99例患者的电子病历。收集的数据包括患者人口统计学信息、潜在病因、临床表现、治疗方法和手术结果。手术病例根据使用标准的帕克手术剂量或增加剂量进行分类,增加剂量定义为超出标准量0.5毫米。还通过统计分析评估了与手术成功结果相关的因素。

结果

诊断时的平均年龄为28.97±19.67岁,男性略占多数。ACE分别被分类为I型(斯旺型)、II型(布里安-弗朗切斯科蒂型)和III型(比尔绍夫斯基型),比例分别为8.08%(8/99)、46.46%(46/99)和45.45%(45/99)。所有病例均为特发性,4.04%(4/99)的患者检测到神经影像学异常。79.8%(79/99)的病例需要手术干预。术后一年,75%(54/72)的患者眼位有显著改善。基于亚组分析,增加剂量组的成功率为91.18%,未增加剂量组为60.53%。逻辑回归分析表明,增加手术剂量与良好的手术结果显著相关(调整后的优势比:5.50;95%置信区间[95%CI],1.32 - 22.89)。

结论

本研究表明ACE患者手术成功率高,支持增加手术剂量的潜在应用。有必要进一步研究以确定其他预后因素并完善治疗策略,以实现ACE的最佳管理。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b029/12258399/6c577b2d446a/OPTH-19-2211-g0001.jpg

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