Algazi V R, Keltner J L, Johnson C A
Invest Ophthalmol Vis Sci. 1985 Dec;26(12):1759-70.
This paper describes two complementary methods for computer analysis of the optic disc in glaucoma. The objective of both techniques is to detect and monitor changes in the optic disc through the use of digital image processing techniques that allow user intervention. In the first method, optic disc photographs from successive years are digitized, scaled and registered (aligned) with each other, and are then displayed in rapid sequence on a television monitor. Changes in the optic cup thus appear as localized movement on the display, while stable regions of the optic cup appear stationary. Both monocular and stereo photographs can be processed by this technique. In the second method, stereo optic disc photographs are digitized and processed by a new, robust, photogrammetric computer algorithm that quantifies optic cup depth information. Together, these two techniques may be valuable for both clinical and research purposes in the detection and monitoring of glaucomatous optic cupping.
本文介绍了两种用于青光眼视盘计算机分析的互补方法。这两种技术的目的都是通过使用允许用户干预的数字图像处理技术来检测和监测视盘的变化。在第一种方法中，连续几年的视盘照片被数字化、缩放并相互配准（对齐），然后在电视监视器上快速连续显示。视杯的变化在显示器上表现为局部运动，而视杯的稳定区域则保持静止。单眼和立体照片都可以用这种技术处理。在第二种方法中，立体视盘照片被数字化，并通过一种新的、强大的摄影测量计算机算法进行处理，该算法可对视杯深度信息进行量化。这两种技术结合起来，在青光眼视杯凹陷的检测和监测的临床和研究目的方面可能都很有价值。
