Effect of concanavalin A on the early events of rabies virus infection of CER cells.
作者信息
Conti C, Tsiang H
出版信息
Intervirology. 1985;24(3):166-9. doi: 10.1159/000149636.
PMID:4066254
Abstract
The effect of concanavalin A on rabies virus infection of CER cells was investigated. Pretreatment of CER cells with concanavalin A inhibited cellular susceptibility to rabies virus infection. The lectin also was found to be inhibitory when applied after the viral binding step. Moreover, the lectin had a direct inhibitory effect on the infectivity of the virion. These lectin-mediated inhibitions could be reversed by alpha-D-methyl-mannopyranoside. These complex effects are discussed with regard to the mechanism of rabies virus entry into CER cells.
摘要
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