Haie C, Schlienger M, Constans J P, Meder J F, Reynaud A, Ghenim C
Int J Radiat Oncol Biol Phys. 1985 Dec;11(12):2051-6. doi: 10.1016/0360-3016(85)90083-5.
From 1961 to 1982, 20 adults (greater than 16 years of age) were treated with radiation therapy following surgery for medulloblastoma. All patients received neuro-axis irradiation. Five patients received adjuvant chemotherapy. A 5- and 10-year survival rate of 78 and 55%, respectively, were achieved. Treatment failures were mainly a result of local recurrences, but also of metastases. One patient died of acute myeloid leukemia. One patient developed paraplegia. The survival rate was better in males (2 deaths out of 14) than in females (5 deaths out of 6). All the survivors are free of deficit or sequelae, except the patient with paraplegia.
1961年至1982年期间,20名成年患者(年龄大于16岁)在髓母细胞瘤手术后接受了放射治疗。所有患者均接受了神经轴照射。5名患者接受了辅助化疗。5年和10年生存率分别为78%和55%。治疗失败主要是局部复发的结果,但也有转移。1名患者死于急性髓系白血病。1名患者出现截瘫。男性的生存率(14例中有2例死亡)高于女性(6例中有5例死亡)。除截瘫患者外,所有幸存者均无功能缺陷或后遗症。