• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

成人髓母细胞瘤的放射治疗结果。

Results of radiation treatment of medulloblastoma in adults.

作者信息

Haie C, Schlienger M, Constans J P, Meder J F, Reynaud A, Ghenim C

出版信息

Int J Radiat Oncol Biol Phys. 1985 Dec;11(12):2051-6. doi: 10.1016/0360-3016(85)90083-5.

DOI:10.1016/0360-3016(85)90083-5
PMID:4066436
Abstract

From 1961 to 1982, 20 adults (greater than 16 years of age) were treated with radiation therapy following surgery for medulloblastoma. All patients received neuro-axis irradiation. Five patients received adjuvant chemotherapy. A 5- and 10-year survival rate of 78 and 55%, respectively, were achieved. Treatment failures were mainly a result of local recurrences, but also of metastases. One patient died of acute myeloid leukemia. One patient developed paraplegia. The survival rate was better in males (2 deaths out of 14) than in females (5 deaths out of 6). All the survivors are free of deficit or sequelae, except the patient with paraplegia.

摘要

1961年至1982年期间,20名成年患者(年龄大于16岁)在髓母细胞瘤手术后接受了放射治疗。所有患者均接受了神经轴照射。5名患者接受了辅助化疗。5年和10年生存率分别为78%和55%。治疗失败主要是局部复发的结果,但也有转移。1名患者死于急性髓系白血病。1名患者出现截瘫。男性的生存率(14例中有2例死亡)高于女性(6例中有5例死亡)。除截瘫患者外,所有幸存者均无功能缺陷或后遗症。

相似文献

1
Results of radiation treatment of medulloblastoma in adults.成人髓母细胞瘤的放射治疗结果。
Int J Radiat Oncol Biol Phys. 1985 Dec;11(12):2051-6. doi: 10.1016/0360-3016(85)90083-5.
2
Hyperfractionated craniospinal radiotherapy and adjuvant chemotherapy for children with newly diagnosed medulloblastoma and other primitive neuroectodermal tumors.超分割全脑全脊髓放疗联合辅助化疗治疗新诊断的儿童髓母细胞瘤及其他原始神经外胚层肿瘤
Int J Radiat Oncol Biol Phys. 1996 Dec 1;36(5):1155-61. doi: 10.1016/s0360-3016(96)00450-6.
3
The change in patterns of relapse in medulloblastoma.髓母细胞瘤复发模式的变化。
Cancer. 1991 Oct 1;68(7):1600-4. doi: 10.1002/1097-0142(19911001)68:7<1600::aid-cncr2820680722>3.0.co;2-v.
4
Cerebellar medulloblastoma in adults.
J Neurosurg. 1984 May;60(5):994-7. doi: 10.3171/jns.1984.60.5.0994.
5
Hyperfractionated craniospinal radiation therapy for primitive neuroectodermal tumors: results of a Phase II study.超分割全脑全脊髓放疗治疗原始神经外胚层肿瘤:一项II期研究的结果
Int J Radiat Oncol Biol Phys. 1999 Jan 15;43(2):279-85. doi: 10.1016/s0360-3016(98)00413-1.
6
Medulloblastoma in adults.成人髓母细胞瘤
Int J Radiat Oncol Biol Phys. 1995 Jul 15;32(4):951-7. doi: 10.1016/0360-3016(94)00612-o.
7
Treatment of high-risk medulloblastoma and other primitive neuroectodermal tumors with reduced dose craniospinal radiation therapy and multi-agent nitrosourea-based chemotherapy.采用降低剂量的全脑全脊髓放射治疗和基于亚硝基脲的多药化疗治疗高危髓母细胞瘤和其他原始神经外胚层肿瘤。
Pediatr Neurosurg. 1996 Oct;25(4):174-81. doi: 10.1159/000121120.
8
Medulloblastoma--treatment and prognosis. A study of seventeen cases in ten years.髓母细胞瘤——治疗与预后。十年间17例病例的研究。
Calif Med. 1973 Jan;118(1):14-7.
9
Medulloblastoma. Treatment results.髓母细胞瘤。治疗结果。
Acta Radiol Oncol Radiat Phys Biol. 1978;17(4):305-11. doi: 10.3109/02841867809127933.
10
Improved survival with the use of adjuvant chemotherapy in the treatment of medulloblastoma.在髓母细胞瘤治疗中使用辅助化疗可提高生存率。
J Neurosurg. 1991 Mar;74(3):433-40. doi: 10.3171/jns.1991.74.3.0433.

引用本文的文献

1
Radiotherapy for adult medulloblastoma: Long term result from a single institution. A review of prognostic factors and why we do need a multi-institutional cooperative program.成人髓母细胞瘤的放射治疗:单机构长期结果。预后因素综述及我们为何需要多机构合作项目。
Rep Pract Oncol Radiother. 2015 Jul-Aug;20(4):284-91. doi: 10.1016/j.rpor.2015.03.003. Epub 2015 Apr 8.
2
Multifocal presentation of medulloblastoma in adulthood.成人大脑髓母细胞瘤的多灶性表现。
J Neurooncol. 2012 Apr;107(2):233-7. doi: 10.1007/s11060-011-0746-7. Epub 2011 Nov 10.
3
The role of radiotherapy in adult medulloblastoma: long-term single-institution experience and a review of the literature.
放疗在成人髓母细胞瘤中的作用:单机构长期经验及文献复习。
J Neurooncol. 2012 Jan;106(2):315-23. doi: 10.1007/s11060-011-0665-7. Epub 2011 Jul 31.
4
Medulloblastoma in adults: a series from Brazil.成人髓母细胞瘤:来自巴西的系列病例
J Neurooncol. 2002 Dec;60(3):247-53. doi: 10.1023/a:1021178518361.
5
Are childhood and adult medulloblastomas different? A comparative study of clinicopathological features, proliferation index and apoptotic index.儿童和成人髓母细胞瘤有差异吗?一项关于临床病理特征、增殖指数和凋亡指数的比较研究。
J Neurooncol. 2002 Aug;59(1):49-61. doi: 10.1023/a:1016357731363.
6
Etoposide-carboplatin association as 'emergency' up-front chemotherapy in a case of life-threatening adult medulloblastoma.
J Neurooncol. 1998 Sep;39(3):253-9. doi: 10.1023/a:1005922625155.
7
Medulloblastoma in late adults: report of two cases and critical review of the literature.老年成人髓母细胞瘤:两例报告及文献综述
J Neurooncol. 1994;19(2):169-73.
8
High dose chemotherapy with stem-cell transplantation in a metastatic medulloblastoma in an adult: a case report and review of the literature.
J Neurooncol. 1994;18(1):19-23. doi: 10.1007/BF01324599.
9
Medulloblastoma in children and in adults: a comparative study.
Acta Neurochir (Wien). 1992;119(1-4):62-7. doi: 10.1007/BF01541783.