Lindemann M D, Kornegay E T, Stahly T S, Cromwell G L, Easter R A, Kerr B J, Lucas D M
J Anim Sci. 1985 Oct;61(4):782-8. doi: 10.2527/jas1985.614782x.
Six trials involving 586 pigs initially averaging 9 kg were conducted at three locations (two trials/location) to evaluate the effects of the dietary addition of 0, 27.5, 55, 82.5 and 110 ppm of a monocarboxylic polyether antibiotic, salinomycin, on feed intake, growth rate and feed efficiency of swine fed corn-soybean meal-based diets. Over the total trial (9 to 97 kg), quadratic improvements in gain (P less than .01) and feed:gain (P less than .04) occurred with increasing level of salinomycin, but feed intake was not affected (P greater than .25). Mean improvements for all drug levels over control values for the total trial were 4.3% for daily gain (P less than .01) and 3.4% for feed:gain (P less than .01). For the total trial, rate and efficiency of gain were optimized in pigs fed the 82.5-ppm level of salinomycin with an improvement of 5.2% in daily gain and 4.8% in feed:gain over pigs fed the control diet. The absence of any significant trial X treatment interaction suggests that the nature of the response was not dependent on differences in environment, management or other factors that existed among trial locations.
在三个地点（每个地点两项试验）进行了六项试验，涉及586头初始平均体重为9千克的猪，以评估在以玉米-豆粕为基础的日粮中添加0、27.5、55、82.5和110 ppm的一元羧酸聚醚抗生素盐霉素对猪的采食量、生长速度和饲料效率的影响。在整个试验期间（9至97千克），随着盐霉素水平的增加，增重（P小于0.01）和料重比（P小于0.04）呈二次改善，但采食量不受影响（P大于0.25）。整个试验中，所有药物水平相对于对照值的平均日增重改善为4.3%（P小于0.01），料重比改善为3.4%（P小于0.01）。在整个试验中，饲喂82.5 ppm盐霉素水平的猪的生长速度和效率达到最佳，与饲喂对照日粮的猪相比，日增重提高了5.2%，料重比提高了4.8%。没有任何显著的试验×处理交互作用表明，反应的性质不取决于试验地点之间存在的环境、管理或其他因素的差异。
