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薄层棒色谱鉴别试验方法在日本药局方制剂中所含药物的应用。

Application of thin-layer stick chromatographic identification test methods to drugs contained in preparations in the pharmacopoeia of Japan.

作者信息

Kawanabe K

出版信息

J Chromatogr. 1985 Sep 27;333(1):115-22. doi: 10.1016/s0021-9673(01)87329-5.

Abstract

A simple, precise technique was developed for identifying the drugs in preparations containing crude drugs listed in the Pharmacopoeia of Japan using thin-layer stick chromatography (TLSC), which is an advanced version of thin layer chromatography in a cylindrical form. The target component in preparations and crude drugs could be detected easily by dipping the developed chromatographic stick in specific colour reagents or by exposure to ultraviolet rays. This technique was applied to the identification of drugs such as salicylic acid, phenol, acrinol and alkaloids and also vitamins contained in the 36 kinds of preparation.

摘要

开发了一种简单、精确的技术,用于使用薄层棒色谱法(TLSC)鉴定含有日本药典中所列生药的制剂中的药物,TLSC是圆柱形形式的薄层色谱的先进版本。通过将展开的色谱棒浸入特定的显色试剂中或暴露于紫外线下,可以轻松检测制剂和生药中的目标成分。该技术应用于36种制剂中所含的水杨酸、苯酚、依沙吖啶、生物碱以及维生素等药物的鉴定。

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