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杜氏肌营养不良症中的神经心理损伤。

Neuropsychological impairment in Duchenne muscular dystrophy.

作者信息

Sollee N D, Latham E E, Kindlon D J, Bresnan M J

出版信息

J Clin Exp Neuropsychol. 1985 Oct;7(5):486-96. doi: 10.1080/01688638508401280.

DOI:10.1080/01688638508401280
PMID:4066905
Abstract

Fourteen younger (ages 6 to 10 years) and 11 older (ages 11 to 16 years) Duchenne Muscular Dystrophy (DMD) patients were tested with the WISC-R and neuropsychological language, visual-motor, and motor tasks. Older boys had an average IQ; younger boys were in the low average IQ range. Younger DMD boys were inferior to the older DMD group on tasks requiring some language and attentional-organizational skills, but not on visual-motor tasks. Older DMD boys were inferior on motor tasks. Results suggest that the reported low cognitive skills in DMD patients are not fixed or global, but reflect selective deficits in the younger boys. Possible bases for age differences in performance are discussed.

摘要

14名年龄较小(6至10岁)和11名年龄较大(11至16岁)的杜氏肌营养不良症(DMD)患者接受了韦氏儿童智力量表修订版(WISC-R)以及神经心理学语言、视觉运动和运动任务测试。年龄较大的男孩智商处于平均水平;年龄较小的男孩智商处于低平均水平范围。在需要一些语言和注意力组织技能的任务上,年龄较小的DMD男孩比年龄较大的DMD组表现差,但在视觉运动任务上并非如此。年龄较大的DMD男孩在运动任务上表现较差。结果表明,报道的DMD患者认知技能较低并非固定不变或全面存在,而是反映出年龄较小男孩存在选择性缺陷。文中讨论了表现出年龄差异的可能原因。

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