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社区居住的艾滋病毒感染者的虚弱状况:一项范围综述方案

Frailty among community-dwelling people living with HIV: a scoping review protocol.

作者信息

Shim Mi-So, Shon Soonyoung, Kim Inah

机构信息

Keimyung University, Daegu, Korea (the Republic of).

Keimyung University, Daegu, Korea (the Republic of)

出版信息

BMJ Open. 2025 Jul 16;15(7):e096254. doi: 10.1136/bmjopen-2024-096254.

DOI:10.1136/bmjopen-2024-096254
PMID:40669909
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12273166/
Abstract

INTRODUCTION

Frailty in people living with HIV is a critical concern due to its significant impact on health, functional capacity and overall quality of life. This scoping review aims to synthesise comprehensive information on frailty in this population, establish foundational evidence and identify research gaps, with particular emphasis on the need for interventions targeting multidimensional frailty among community-dwelling people living with HIV.

METHODS AND ANALYSIS

This scoping review adheres to the Joanna Briggs Institute guidelines and the framework developed by Arksey and O'Malley. The research questions will focus on frailty among community-dwelling people living with HIV. The literature search will encompass four databases: MEDLINE, Embase, CINAHL and the Cochrane Library, covering studies published from 1 January 2001 to 30 June 2025. Only peer-reviewed articles published in English will be included. Both quantitative and qualitative studies will be considered. The inclusion criteria will be guided by the population-conceptual-context (PCC) framework. The findings will be reported in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses Extension for Scoping Reviews checklist.

ETHICS AND DISSEMINATION

Ethical approval is not required as this study involves an analysis of previously published literature. The findings will inform the development of interventions for frailty in people living with HIV and will be disseminated through academic conferences, peer-reviewed publications and expert seminars.

摘要

引言

由于虚弱对艾滋病毒感染者的健康、功能能力和整体生活质量有重大影响,因此这一问题备受关注。本综述旨在综合有关该人群虚弱状况的全面信息,建立基础证据并识别研究空白,尤其强调针对社区居住的艾滋病毒感染者多维虚弱状况进行干预的必要性。

方法与分析

本综述遵循乔安娜·布里格斯研究所指南以及阿克西和奥马利制定的框架。研究问题将聚焦于社区居住的艾滋病毒感染者的虚弱状况。文献检索将涵盖四个数据库:医学文献数据库(MEDLINE)、荷兰医学文摘数据库(Embase)、护理学与健康领域数据库(CINAHL)和考科蓝图书馆,涵盖2001年1月1日至2025年6月30日发表的研究。仅纳入以英文发表的同行评审文章。定量和定性研究均会被考虑在内。纳入标准将以人群 - 概念 - 背景(PCC)框架为指导。研究结果将按照系统评价与Meta分析扩展版范围综述的首选报告项目清单进行报告。

伦理与传播

由于本研究涉及对先前发表文献的分析,因此无需伦理批准。研究结果将为艾滋病毒感染者虚弱状况干预措施的制定提供参考,并将通过学术会议、同行评审出版物和专家研讨会进行传播

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3ea9/12273166/77f4ed8577db/bmjopen-15-7-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3ea9/12273166/77f4ed8577db/bmjopen-15-7-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3ea9/12273166/77f4ed8577db/bmjopen-15-7-g001.jpg

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本文引用的文献

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Health problems and challenges due to aging among people living with HIV aged 50 and older: a qualitative study.50岁及以上HIV感染者因衰老导致的健康问题与挑战:一项定性研究
BMC Public Health. 2025 Jun 6;25(1):2122. doi: 10.1186/s12889-025-23252-8.
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"I'm in the Care Orbit": Unveiling the Enabling Context of the HIV Care Continuum in People Living With HIV.“我处于关怀轨道中”:揭示艾滋病毒感染者艾滋病毒关怀连续体的促成背景。
Nurs Inq. 2025 Jan;32(1):e12695. doi: 10.1111/nin.12695.
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Stigma, isolation, and depression among older adults living with HIV in rural areas.
农村地区感染艾滋病毒的老年人中的耻辱感、孤立感和抑郁情绪。
Ageing Soc. 2020 Jun;40(6):1352-1370. doi: 10.1017/s0144686x18001782. Epub 2019 Jan 24.
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HIV-Related Stigma and Multidimensional Frailty Among Older Latinos With HIV.HIV 相关污名与 HIV 老年拉丁裔人群的多维脆弱性
Hisp Health Care Int. 2024 Jun;22(2):99-108. doi: 10.1177/15404153231208130. Epub 2023 Oct 19.
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Use of the Tilburg frailty indicator in longitudinal studies with older adults: A scoping review.使用蒂尔堡虚弱指标进行老年人纵向研究:范围综述。
J Adv Nurs. 2023 Jul;79(7):2429-2443. doi: 10.1111/jan.15675. Epub 2023 Apr 19.
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A moderated mediation analysis of depression and age on the relationship between resilience and frailty among HIV-positive adults.一项关于抑郁症和年龄对 HIV 阳性成年人的韧性与脆弱性之间关系的调节中介分析。
Front Public Health. 2023 Mar 23;11:1128309. doi: 10.3389/fpubh.2023.1128309. eCollection 2023.
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Life expectancy after 2015 of adults with HIV on long-term antiretroviral therapy in Europe and North America: a collaborative analysis of cohort studies.2015 年后在欧洲和北美接受长期抗逆转录病毒治疗的艾滋病毒感染者的预期寿命:队列研究的协作分析。
Lancet HIV. 2023 May;10(5):e295-e307. doi: 10.1016/S2352-3018(23)00028-0. Epub 2023 Mar 20.
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Biological Aging in People Living with HIV on Successful Antiretroviral Therapy: Do They Age Faster?成功接受抗逆转录病毒疗法的 HIV 感染者的生物学衰老:他们衰老得更快吗?
Curr HIV/AIDS Rep. 2023 Apr;20(2):42-50. doi: 10.1007/s11904-023-00646-0. Epub 2023 Jan 25.
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HIV-Associated Conditions in Older Adults.老年人中的人类免疫缺陷病毒相关病症
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