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房室交界区(“房室结”)折返性心动过速的根治性手术

Curative surgery for atrioventricular junctional ("AV nodal") reentrant tachycardia.

作者信息

Ross D L, Johnson D C, Denniss A R, Cooper M J, Richards D A, Uther J B

出版信息

J Am Coll Cardiol. 1985 Dec;6(6):1383-92. doi: 10.1016/s0735-1097(85)80229-1.

Abstract

A new surgical approach was studied prospectively in 10 consecutive patients with atrioventricular (AV) junctional reentrant tachycardia. The aim was to abolish tachycardia yet preserve normal AV conduction. On the basis of electrophysiologic study before operation, patients were classified as type A (ventriculoatrial [VA] intervals during tachycardia less than or equal to 40 ms) (seven patients) or type B (VA intervals greater than 40 ms) (three patients). Dual AV junctional pathways were demonstrable with single extrastimulus testing in seven patients before operation. Endocardial mapping during tachycardia at surgery revealed earliest atrial activation anteromedial to the AV node in type A patients and posterior to the node in the type B patients. The perinodal atrium in the region of earliest atrial activation during tachycardia was carefully disconnected from the AV node. After operation, AV junctional reentrant tachycardia was not inducible at comprehensive electrophysiologic study in any patient, and no clinical recurrences have occurred during a follow-up period of 2 to 14 months (mean 8 +/- 4). Normal AV conduction was preserved in all cases. Anterograde slow AV junctional pathway conduction was abolished in five of seven cases. Retrograde His to atrium conduction time was prolonged in type A patients but the capacity for retrograde VA conduction remained excellent. Retrograde His to atrium conduction was interrupted or severely compromised in the type B patients. These data show that there are at least two types of AV junctional reentry. Perinodal atrium appears to be part of the reentrant circuit in human AV junctional reentry. Although the most consistent effect of surgery was on the retrograde limb of the circuit, anterograde slow pathway conduction was also modified. AV junctional reentry is surgically curable with a high success rate.

摘要

对10例连续性房室结折返性心动过速患者进行了一项新手术方法的前瞻性研究。目的是消除心动过速,同时保留正常的房室传导。根据术前电生理研究,患者被分为A型(心动过速时室房[VA]间期小于或等于40毫秒)(7例)或B型(VA间期大于40毫秒)(3例)。术前7例患者通过单次额外刺激试验可显示双房室结通路。手术时心动过速期间的心内膜标测显示,A型患者最早的心房激动位于房室结前内侧,B型患者位于房室结后方。在心动过速期间最早心房激动区域的结周心房被小心地与房室结分离。术后,所有患者在全面电生理研究中均不能诱发房室结折返性心动过速,在2至14个月(平均8±4)的随访期内无临床复发。所有病例均保留了正常的房室传导。7例中有5例消除了房室结前向慢径传导。A型患者逆行希氏束至心房的传导时间延长,但逆行VA传导能力仍极佳。B型患者逆行希氏束至心房的传导中断或严重受损。这些数据表明至少有两种类型的房室结折返。结周心房似乎是人类房室结折返折返环的一部分。虽然手术最一致的效果是作用于折返环的逆行支,但前向慢径传导也得到了改善。房室结折返经手术可治愈,成功率高。

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