Remon Jonathan, Diesing Jessica M, Boileau Andrew J
Medicine, Saba University School of Medicine, The Bottom, BES.
Neuroscience and Neurology, Saba University School of Medicine, The Bottom, BES.
Cureus. 2025 Jun 15;17(6):e86050. doi: 10.7759/cureus.86050. eCollection 2025 Jun.
Selective laser trabeculoplasty (SLT) significantly lowers the intraocular pressure (IOP) in open-angle glaucoma patients compared to pattern scanning laser trabeculoplasty (PSLT). This review contains results from randomized control trials and a retrospective database analysis obtained through PubMed and Google Scholar. PubMed searches used the following words and terms: "selective laser trabeculoplasty" AND "pattern scanning trabeculoplasty." A similar search on Google Scholar eventually uncovered one additional study comparing the two trabeculoplasty methods. All studies included patients diagnosed with primary open-angle glaucoma (POAG) or ocular hypertension. SLT has not consistently shown superiority over PSLT in managing POAG. PSLT may result in slightly greater short-term reductions in IOP. Patients often report less discomfort with this method, suggesting it may be more tolerable. Both treatments can lead to meaningful reductions in IOP from baseline, which is generally considered a positive treatment outcome. SLT and PSLT were shown to exert the same efficacy. In terms of treatment, both procedures are efficient and beneficial for lowering IOP. PSLT was favored to be more tolerable in one of the studies. Further research is required to observe potential side effects, long-term treatment, and mechanisms of action of both lasers.
与模式扫描激光小梁成形术(PSLT)相比,选择性激光小梁成形术(SLT)能显著降低开角型青光眼患者的眼压(IOP)。本综述包含通过PubMed和谷歌学术搜索获得的随机对照试验结果以及回顾性数据库分析。PubMed搜索使用了以下词汇和术语:“选择性激光小梁成形术”和“模式扫描小梁成形术”。在谷歌学术上进行的类似搜索最终又发现了一项比较这两种小梁成形术方法的研究。所有研究均纳入了被诊断为原发性开角型青光眼(POAG)或高眼压症的患者。在治疗POAG方面,SLT并未始终显示出优于PSLT的效果。PSLT可能会使眼压在短期内稍有更大幅度的降低。患者通常报告称这种方法带来的不适较少,这表明它可能更易于耐受。两种治疗方法均可使眼压较基线水平有显著降低,这通常被视为积极的治疗结果。SLT和PSLT显示出相同的疗效。在治疗方面,两种手术对于降低眼压都是有效且有益的。在其中一项研究中,PSLT被认为更易于耐受。需要进一步研究以观察两种激光的潜在副作用、长期治疗效果及作用机制。