Yokoi Katsunori, Suzuki Keisuke, Yamaoka Akiko, Katsuno Masahisa, Arahata Yutaka
Department of Neurology, National Center for Geriatrics and Gerontology, Obu, JPN.
Department of Neurology, Nagoya University Graduate School of Medicine, Nagoya, JPN.
Cureus. 2025 Jun 16;17(6):e86109. doi: 10.7759/cureus.86109. eCollection 2025 Jun.
Orthostatic hypotension (OH) is a common non-motor complication of Parkinson's disease (PD), significantly affecting the quality of life and increasing fall risk. While pharmacological treatments are available, their efficacy is often limited. Abdominal belts have been proposed as a non-pharmacological intervention, but their effects on blood pressure (BP) fluctuations remain unclear. In this case series, we examined four patients with PD and OH, all of whom underwent 24-hour ambulatory BP monitoring (ABPM) before and after using an abdominal belt. The belt was applied with a pressure of 20 ± 2 mmHg and worn during waking hours. The mean systolic BP (SBP) and diastolic BP (DBP) during daytime and nighttime were compared using the Mann-Whitney U test. BP variability was assessed. Three patients demonstrated improved BP stability with abdominal belt use, particularly in reducing postprandial hypotension. One patient (Case 1) discontinued use due to discomfort and showed no significant BP changes. In Case 3, SBP increased from 117.85 ± 5.92 mmHg to 162.74 ± 10.80 mmHg (p = 0.002), and DBP from 66.35 ± 3.36 mmHg to 91.19 ± 5.24 mmHg (p = 0.001). Case 4 also exhibited a significant increase in SBP (p = 0.005). However, BP fluctuations persisted, and nocturnal BP remained unchanged. We concluded that the use of an abdominal belt may help stabilize BP in patients with PD and OH during daytime activities, but does not eliminate BP variability. Studies with more patients are needed to confirm these findings and refine recommendations for abdominal belt use in PD management.
直立性低血压(OH)是帕金森病(PD)常见的非运动并发症,显著影响生活质量并增加跌倒风险。虽然有药物治疗方法,但其疗效往往有限。腹带已被提议作为一种非药物干预措施,但其对血压(BP)波动的影响仍不清楚。在这个病例系列中,我们检查了4例患有PD和OH的患者,他们在使用腹带前后均接受了24小时动态血压监测(ABPM)。腹带施加的压力为20±2 mmHg,在清醒时间佩戴。使用Mann-Whitney U检验比较白天和夜间的平均收缩压(SBP)和舒张压(DBP)。评估血压变异性。3例患者使用腹带后血压稳定性得到改善,特别是在减少餐后低血压方面。1例患者(病例1)因不适而停止使用,血压无明显变化。在病例3中,SBP从117.85±5.92 mmHg升高至162.74±10.80 mmHg(p = 0.002),DBP从66.35±3.36 mmHg升高至91.19±5.24 mmHg(p = 0.001)。病例4的SBP也显著升高(p = 0.005)。然而,血压波动仍然存在,夜间血压保持不变。我们得出结论,使用腹带可能有助于在白天活动期间稳定PD和OH患者的血压,但不能消除血压变异性。需要更多患者的研究来证实这些发现,并完善在PD管理中使用腹带的建议。