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迟发性罗阿丝虫病:一例暴露后六年确诊的罗阿罗阿丝虫感染病例。

Delayed-Onset Loiasis: A Case of Loa loa Infection Diagnosed Six Years Post-exposure.

作者信息

Root Halle N, Bueno Diana, Bathurst Nicholas, Wieting Michael

机构信息

Medical School, Lincoln Memorial University, DeBusk College of Osteopathic Medicine, Knoxville, USA.

Medical School, Lincoln Memorial University, DeBusk College of Osteopathic Medicine, Harrogate, USA.

出版信息

Cureus. 2025 Jun 16;17(6):e86135. doi: 10.7759/cureus.86135. eCollection 2025 Jun.

Abstract

Loiasis, caused by , is a filarial infection endemic to Central and West Africa, increasingly recognized in non-endemic regions due to global migration and travel. Diagnosis in non-endemic regions can be challenging due to delayed symptom onset. We report a case of a 40-year-old woman presenting with ocular discomfort and a migrating subcutaneous parasite six years after residing in Gabon. Laboratory evaluation revealed eosinophilia and microfilariae on peripheral blood smear, confirming loiasis. Initial treatment with albendazole led to inflammatory symptoms, highlighting the risk of post-treatment reactions. This case underscores the importance of recognizing loiasis in patients with remote travel history, the need for careful microfilarial burden assessment, and multidisciplinary management to optimize treatment outcomes.

摘要

罗阿丝虫病由[具体病原体未给出]引起,是中非和西非特有的一种丝虫感染,由于全球移民和旅行,在非流行地区越来越多地被认识到。由于症状出现延迟,非流行地区的诊断可能具有挑战性。我们报告一例40岁女性病例,该患者在加蓬居住6年后出现眼部不适和皮下移行寄生虫。实验室检查显示外周血涂片嗜酸性粒细胞增多和微丝蚴,确诊为罗阿丝虫病。阿苯达唑初始治疗导致炎症症状,突出了治疗后反应的风险。该病例强调了在有远程旅行史的患者中识别罗阿丝虫病的重要性,需要仔细评估微丝蚴负荷,以及多学科管理以优化治疗结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/956e/12266084/88dc3cbcf02a/cureus-0017-00000086135-i01.jpg

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