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内镜下机械碎石术成功治疗ERCP术后胆石性肠梗阻:一例报告

Successful endoscopic mechanical lithotripsy for post-ERCP gallstone ileus: a case report.

作者信息

Wang Jing, Luan Zhe, Yan Bin, Sun Gang

机构信息

Department of Gastroenterology and Hepatology, First Medical Center, Chinese PLA General Hospital, Beijing, China.

School of Medicine, Nankai University, Tianjin, China.

出版信息

Front Med (Lausanne). 2025 Jul 2;12:1604835. doi: 10.3389/fmed.2025.1604835. eCollection 2025.

DOI:10.3389/fmed.2025.1604835
PMID:40672812
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12263398/
Abstract

Gallstone ileus is a rare but severe complication of gallstone disease and is typically caused by the formation of a fistula between the biliary and gastrointestinal systems. The conventional treatment approach is enterolithotomy with stone removal. However, for elderly patients or those with underlying comorbidities, surgical intervention poses significant risks. Therefore, exploring minimally invasive, nonsurgical treatment strategies holds critical clinical value. A 63-year-old female was admitted to the hospital due to abdominal pain, chills, and high fever. She was diagnosed with a large common bile duct stone (diameter 3.9 cm). During endoscopic retrograde cholangiopancreatography (ERCP), as the stone was too large to be removed directly, endoscopic sphincterotomy (EST) combined with the placement of a biliary plastic stent was performed. On the 7th postoperative day, the patient developed nausea, vomiting, and constipation. Laboratory tests revealed elevated inflammatory marker, pancreatic enzyme, bile enzyme, and bilirubin levels. Imaging studies revealed intestinal dilatation and a high-density shadow within the intestinal lumen, leading to the diagnosis of gallstone ileus. On postoperative day 11, biliary and pancreatic stents were placed. On postoperative day 16, endoscopic stone extraction was attempted, successfully relieving the obstruction. The patient recovered well postoperatively and experienced no recurrence during the 2-month follow-up. This case report describes the successful treatment of post-ERCP gallstone ileus using endoscopic stone extraction and fragmentation techniques.

摘要

胆石性肠梗阻是胆石症一种罕见但严重的并发症,通常由胆道系统与胃肠道系统之间形成瘘管所致。传统的治疗方法是行肠石切除术并取出结石。然而,对于老年患者或有基础合并症的患者,手术干预存在重大风险。因此,探索微创、非手术治疗策略具有关键的临床价值。一名63岁女性因腹痛、寒战和高热入院。她被诊断为胆总管巨大结石(直径3.9厘米)。在内镜逆行胰胆管造影术(ERCP)期间,由于结石太大无法直接取出,遂行内镜括约肌切开术(EST)并置入胆道塑料支架。术后第7天,患者出现恶心、呕吐和便秘。实验室检查显示炎症标志物、胰酶、胆汁酶和胆红素水平升高。影像学检查显示肠扩张和肠腔内高密度影,从而诊断为胆石性肠梗阻。术后第11天,置入胆道和胰腺支架。术后第16天,尝试内镜下取石,成功解除梗阻。患者术后恢复良好,在2个月的随访期间未复发。本病例报告描述了使用内镜下取石和碎石技术成功治疗ERCP术后胆石性肠梗阻的情况。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8827/12263398/16d19b81ac06/fmed-12-1604835-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8827/12263398/5e4349c78c77/fmed-12-1604835-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8827/12263398/16d19b81ac06/fmed-12-1604835-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8827/12263398/5e4349c78c77/fmed-12-1604835-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8827/12263398/16d19b81ac06/fmed-12-1604835-g002.jpg

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本文引用的文献

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