Suppr超能文献

勒米尔综合征中肺脓毒性栓塞与肺动脉血栓栓塞的关联:一例报告及文献综述

Association of Pulmonary Septic Embolism and Pulmonary Arterial Thromboembolism in Lemierre Syndrome: A Case Report and Literature Review.

作者信息

Fabozzi Antonio, Siena Alessandro, Steffanina Alessia, Iannuzzi Silvia, Bonini Matteo, Palange Paolo

机构信息

Department of Public Health and Infectious Diseases, Pulmonology Unit, Policlinico Umberto I "Sapienza" University of Rome Rome Italy.

出版信息

Respirol Case Rep. 2025 Jul 15;13(7):e70266. doi: 10.1002/rcr2.70266. eCollection 2025 Jul.

Abstract

Lemierre syndrome (LS) is a rapidly progressing disease characterised by a recent oropharyngeal infection, complicated by septic emboli and thrombophlebitis of the internal jugular vein (IJV). We describe a case of a 65-year-old woman who presented to the emergency room with a 14-day history of progressive occipital headache, fever and odynophagia. Radiological investigations showed bilateral IJV thrombophlebitis, multiple cavitated pulmonary nodules suggestive of septic emboli and a subsegmental pulmonary arterial thromboembolism. A diagnosis of LS was made. The patient received antibiotic treatment with intravenous ceftriaxone and clindamycin for 2 weeks, followed by 4 weeks of oral clindamycin at home and anticoagulation with enoxaparin followed by warfarin. One-month follow-up imaging revealed complete resolution of IJV thrombosis and pulmonary findings. This case displayed the rarely reported association of pulmonary arterial thromboembolism and pulmonary septic emboli.

摘要

勒米尔综合征(LS)是一种进展迅速的疾病,其特征为近期有口咽感染,并伴有脓毒性栓子和颈内静脉(IJV)血栓性静脉炎。我们报告一例65岁女性,因进行性枕部头痛、发热和吞咽痛14天就诊于急诊室。影像学检查显示双侧IJV血栓性静脉炎、多个有空洞的肺结节提示脓毒性栓子以及亚段肺动脉血栓栓塞。诊断为LS。患者接受了静脉注射头孢曲松和克林霉素抗生素治疗2周,随后在家口服克林霉素4周,并使用依诺肝素抗凝,之后改为华法林抗凝。1个月的随访影像学检查显示IJV血栓形成和肺部病变完全消退。该病例展示了肺动脉血栓栓塞与肺脓毒性栓子之间罕见的关联。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8935/12263511/6a437dcdf7ab/RCR2-13-e70266-g002.jpg

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验