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用于评估二尖瓣置换患者的数字灌注图像

[Digital perfusion images for evaluating patients with mitral valve replacement].

作者信息

Tanaka T, Suzuki S, Aosaki M, Horie T, Takahashi S, Kimata S, Kondo M, Hirosawa K, Kusakabe K, Shigeta T

出版信息

J Cardiogr. 1985 Mar;15(1):89-99.

PMID:4067351
Abstract

To determine whether the distribution of pulmonary perfusion can be applied as a noninvasive means of evaluating patients with mitral valve replacement (MVR), computerized Tc-99m MAA pulmonary perfusion images (digital perfusion images: DPI) were obtained for 32 patients in the preoperative, early postoperative and late postoperative (18 months mean) periods. DPI consisted of isocount areas, and a 100-70% area was defined as a hyperperfusion area. The distribution of pulmonary perfusion was evaluated using patterns of hyperperfusion area in anterior DPI. In 32 patients above-mentioned had the hyperperfusion areas in the upper lung fields preoperatively, the perfusion of the lung base was investigated. In 21 patients hyperperfusion area appeared in the lung base in the late follow-up period (group A), and all patients improved clinically. In 11 patients, the DPI improved to nearly normal patterns. In five patients, the DPI improved after one year postoperatively. In 11 patients, hyperperfusion areas did not appear in the lung base in the late follow-up period (group B). Six of the 11 patients did not improve clinically. There were no significant hemodynamic differences between groups A and B except for slight differences in the postoperative pulmonary vascular resistance. These results suggested significant correlations between the clinical improvement and the normalization of the DPI. The use of DPI patterns may facilitate quantitative and objective estimations of postoperative states. Since DPI are easy to perform noninvasively, DPI may comprise a useful graphic diagnostic method for evaluating patients with MVR.

摘要

为了确定肺灌注分布是否可作为评估二尖瓣置换术(MVR)患者的一种非侵入性方法,我们获取了32例患者术前、术后早期和术后晚期(平均18个月)的计算机化Tc-99m MAA肺灌注图像(数字灌注图像:DPI)。DPI由等计数区域组成,100 - 70%的区域被定义为高灌注区域。使用前位DPI中高灌注区域的模式来评估肺灌注分布。上述32例患者术前上肺野有高灌注区域,对其肺底部灌注情况进行了研究。21例患者在随访后期肺底部出现高灌注区域(A组),所有患者临床症状均有改善。11例患者中,DPI改善至接近正常模式。5例患者术后1年DPI改善。11例患者在随访后期肺底部未出现高灌注区域(B组)。11例患者中有6例临床症状未改善。除术后肺血管阻力略有差异外,A组和B组之间无显著血流动力学差异。这些结果表明临床改善与DPI正常化之间存在显著相关性。使用DPI模式可能有助于对术后状态进行定量和客观评估。由于DPI易于非侵入性地进行,DPI可能是一种用于评估MVR患者的有用的图像诊断方法。

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