Gollmann-Tepeköylü Can, Berretta Paolo, Gerdisch Marc, Cresce Giovanni D, Kempfert Jörg, Pitsis Antonios, Van Praet Frank, Rinaldi Mauro, Wilbring Manuel, Yan Tristan, Pacini Davide, Doenst Torsten, Fiore Antonio, Dinh Nguyen Hoang, Lamelas Joseph, Stefano Pierluigi, Nguyen Tom C, Bonaros Nikolaos, Di Eusanio Marco
Department of Cardiac Surgery, Medical University of Innsbruck, Innsbruck, Austria.
Cardiac Surgery Unit, Lancisi Cardiovascular Center, Polytechnic University of Marche, Ancona, Italy.
Eur J Cardiothorac Surg. 2025 Jul 1;67(7). doi: 10.1093/ejcts/ezaf201.
To identify factors influencing the decision to omit tricuspid valve repair in patients who meet guideline criteria for tricuspid valve repair undergoing minimally invasive mitral valve surgery (MIMVS).
A retrospective analysis was conducted using the MIMVS International Registry, covering 7513 patients from 17 centres in Europe USA, Asia and Australia. Of these, 1077 had an indication for tricuspid valve repair. Patients were stratified into two groups: those who underwent tricuspid valve repair (n = 910) and those who did not (n = 167). Multivariate logistic regression analysis was conducted to identify the factors associated with the decision to perform tricuspid valve repair.
Patients who received tricuspid valve repair were older (72 vs 67 years, P < 0.001), more often female (53.8% vs 39.8%, P < 0.001) and had higher rates of atrial fibrillation (70.1% vs 54%, P < 0.001). Tricuspid valve repair was associated with longer ICU (48 vs 23 hours, P < 0.001) and hospital stays (11 vs 8 days, P < 0.001), but 30-day mortality was similar between groups (4.3% for tricuspid valve repair vs 1.8% for no tricuspid valve repair, P = 0.2). Patients undergoing tricuspid valve repair had higher EuroSCORE II (2.9 vs 1.6, P < 0.001). Key factors for omitting tricuspid valve repair included absence of severe tricuspid regurgitation (odds ratio [OR] 3.31 for moderate tricuspid regurgitation; OR 4.06 for mild tricuspid regurgitation), lower NYHA class (OR 0.61 for NYHA III-IV), and mitral valve disease type (OR 0.38) and institutional practices (SD 0.28).
Prophylactic indications for concomitant tricuspid valve repair in MIMVS are generally followed. Clinical and institutional factors strongly influence the decision to omit the tricuspid procedure despite guideline recommendations. Adhering to guidelines may improve outcomes by standardizing treatment choices.
确定在接受微创二尖瓣手术(MIMVS)且符合三尖瓣修复指南标准的患者中,影响不进行三尖瓣修复决策的因素。
使用MIMVS国际注册中心的数据进行回顾性分析,涵盖来自欧洲、美国、亚洲和澳大利亚17个中心的7513例患者。其中,1077例有三尖瓣修复指征。患者被分为两组:接受三尖瓣修复的患者(n = 910)和未接受三尖瓣修复的患者(n = 167)。进行多因素逻辑回归分析以确定与进行三尖瓣修复决策相关的因素。
接受三尖瓣修复的患者年龄更大(72岁对67岁,P < 0.001),女性比例更高(53.8%对39.8%,P < 0.001),房颤发生率更高(70.1%对54%,P < 0.001)。三尖瓣修复与更长的重症监护病房(ICU)住院时间(48小时对23小时,P < 0.001)和住院时间(11天对8天,P < 0.001)相关,但两组间30天死亡率相似(三尖瓣修复组为4.3%,未进行三尖瓣修复组为1.8%,P = 0.2)。接受三尖瓣修复的患者欧洲心脏手术风险评估系统(EuroSCORE)II评分更高(2.9对1.6,P < 0.001)。不进行三尖瓣修复的关键因素包括无严重三尖瓣反流(中度三尖瓣反流的比值比[OR]为3.31;轻度三尖瓣反流的OR为4.06)、纽约心脏协会(NYHA)心功能分级较低(NYHA III-IV级的OR为0.61)、二尖瓣疾病类型(OR为0.38)以及机构实践(标准差为0.28)。
MIMVS中同期进行三尖瓣修复的预防性指征通常会被遵循。尽管有指南推荐,但临床和机构因素强烈影响不进行三尖瓣手术的决策。遵循指南可能通过规范治疗选择来改善预后。