Liu Wansu, Gong Xionghu, Shang Jingge, Qin Yu, Yao Xiaolong, Wang Zhaode, Liu Xiaohui, Gao Guang, Zhang Lu, Zhao Zhonghua
State Key Laboratory of Lake and Watershed Science for Water Security, Nanjing Institute of Geography and Limnology, Chinese Academy of Sciences, Nanjing, 210008, China; University of Chinese Academy of Sciences, Nanjing, 211135, China.
School of Engineering, China Pharmaceutical University, Nanjing, 211198, China.
J Environ Manage. 2025 Sep;391:126556. doi: 10.1016/j.jenvman.2025.126556. Epub 2025 Jul 16.
Although most previous studies have illustrated the fate of antibiotics in specific lakes, little is known about their distribution from a nationwide scale due to the insufficient knowledge in arid zones, not even to mention declaring the possible impacts driven by both the climate change and anthropogenic activities. To fill this gap, we selected several typical lakes located in arid region of northwestern China-Xinjiang to assess the occurrence and risks of antibiotics in water and sediment, and then to identity the possible influences of parameters focusing on climate change and anthropogenic activities by comparing with lakes from humid zones. Firstly, 29 kinds of antibiotics were 100 % observed in all arid lakes showing highest level of 506.8 ng/L for water and 22.5 ng/g for sediment with fluoroquinolones (57.6 %) and tetracyclines (36.9 %) being the predominant compositions. The spatial heterogeneity of antibiotic distribution within lakes in arid regions is primarily attributed to factors such as salinity and the physicochemical properties of compounds, whereas the differences between arid and humid regions are mainly driven by temperature and precipitation, which can be inferred by the Antibiotic Normalized Volume Load (ANVL) index used for evaluating the persistence of antibiotics in lakes. Ecologic risks conducted by risk quotients (RQs) and sediment quality index (SeQI) indicated lakes in arid zones were facing high risks than others. Therefore, establishing an ecological zoning control system for antibiotics, not only helps preserve the quality and sustainability of water resources but also safeguards the ecological functions and biodiversity of arid region lakes.
尽管此前大多数研究都阐述了抗生素在特定湖泊中的归宿，但由于对干旱地区了解不足，目前对于抗生素在全国范围内的分布情况知之甚少，更遑论说明气候变化和人类活动可能带来的影响。为填补这一空白，我们选取了中国西北干旱地区——新疆的几个典型湖泊，评估水和沉积物中抗生素的存在情况及风险，然后通过与湿润地区湖泊对比，确定聚焦于气候变化和人类活动的参数可能产生的影响。首先，在所有干旱湖泊中均检测到了29种抗生素，水体中抗生素含量最高达506.8纳克/升，沉积物中为22.5纳克/克，其中氟喹诺酮类（57.6%）和四环素类（36.9%）为主要成分。干旱地区湖泊内抗生素分布的空间异质性主要归因于盐度和化合物的理化性质等因素，而干旱地区与湿润地区之间的差异主要由温度和降水驱动，这可通过用于评估湖泊中抗生素持久性的抗生素归一化体积负荷（ANVL）指数推断得出。通过风险商数（RQs）和沉积物质量指数（SeQI）进行的生态风险评估表明，干旱地区的湖泊面临着比其他地区更高的风险。因此，建立抗生素生态分区控制系统，不仅有助于保护水资源的质量和可持续性，还能保障干旱地区湖泊的生态功能和生物多样性。
