Perper J A
J Forensic Sci. 1985 Oct;30(4):1248-55.
A typical case of suicidal strychnine poisoning by a rodenticide is presented. The forceful muscular convulsions were accompanied by a clear sensorium. Pathological findings consisted of an early onset of postmortem rigidity and microscopic hemorrhages with minimal degenerative neuronal changes in the spinal cord. The highest tissue concentrations of strychnine were found in the bile and liver. The pathophysiology and epidemiology of strychnine poisoning is reviewed and discussed in context.
本文介绍了一例典型的因灭鼠剂导致的士的宁自杀中毒病例。剧烈的肌肉抽搐伴有意识清醒。病理检查结果包括死后早期尸僵以及脊髓微小的退行性神经元变化和微观出血。胆汁和肝脏中的士的宁组织浓度最高。本文结合实际情况对士的宁中毒的病理生理学和流行病学进行了综述和讨论。
