Chen Ying-Xiang, Zhou You, Zhang Xiao-Lan, He Wen-Yan, Ye Qin, Xu Min
Nursing Department, The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), Hangzhou, Zhejiang, China.
Digit Health. 2025 Jul 15;11:20552076251358297. doi: 10.1177/20552076251358297. eCollection 2025 Jan-Dec.
Breast cancer is a common malignancy among women worldwide, frequently associated with cancer-related cognitive impairment, which significantly affects quality of life. Non-pharmacological therapies, especially digital health interventions (DHIs), show potential in mitigating cognitive impairment related to cancer through tailored and interactive cognitive training. Nonetheless, current research fails to systematically integrate intervention strategies, behavioral change techniques (BCTs), and their effectiveness.
This scoping review sought to delineate existing DHIs for cognitive impairment related to cancer in breast cancer patients, emphasizing intervention attributes, efficacy, and the use of behavior change techniques to guide future research and clinical practice.
Following Arksey and O'Malley's framework, nine databases were systematically searched (inception to February 2025). Inclusion criteria were defined using PICOS (Population, Intervention, Comparison, Outcomes, Study design). Data on intervention characteristics, BCTs, and outcomes were extracted and analyzed via Michie's BCT taxonomy.
Nineteen studies were incorporated. DHIs predominantly employed computerized cognitive training (78.94%), virtual reality (VR) (15.78%), and robotics (5.26%). Prominent BCTs encompassed goal setting (100%), feedback/monitoring (89%), and social support (100%). Eighteen investigations indicated substantial cognitive enhancement, six saw better emotional well-being, and two evidenced an elevated quality of life. Gamification and VR therapies resulted in elevated patient adherence and satisfaction.
DHIs significantly enhance Cognitive Rehabilitation and Cognitive Impairment through cognitive training and multifaceted BCTs. Challenges encompass diverse study designs, insufficient long-term data, and technical obstacles. Future research must include standardized cognitive evaluations, longitudinal investigations, and initiatives to address the digital divide.
乳腺癌是全球女性中常见的恶性肿瘤，常与癌症相关的认知障碍有关，这会显著影响生活质量。非药物疗法，尤其是数字健康干预措施（DHIs），通过量身定制的交互式认知训练，在减轻与癌症相关的认知障碍方面显示出潜力。然而，目前的研究未能系统地整合干预策略、行为改变技术（BCTs）及其有效性。
本范围综述旨在描述现有的针对乳腺癌患者癌症相关认知障碍的数字健康干预措施，强调干预属性、疗效以及行为改变技术的应用，以指导未来的研究和临床实践。
按照阿克斯西和奥马利的框架，系统检索了九个数据库（从起始到2025年2月）。纳入标准使用PICOS（人群、干预措施、对照、结局、研究设计）来定义。通过米基的BCT分类法提取并分析了关于干预特征、BCTs和结局的数据。
纳入了19项研究。数字健康干预措施主要采用计算机化认知训练（78.94%）、虚拟现实（VR）（15.78%）和机器人技术（5.26%）。突出的BCTs包括目标设定（100%）、反馈/监测（89%）和社会支持（100%）。18项研究表明认知有显著改善，6项研究显示情绪幸福感有所提高，2项研究证明生活质量有所提升。游戏化和VR疗法提高了患者的依从性和满意度。
数字健康干预措施通过认知训练和多方面的行为改变技术显著增强了认知康复和认知障碍。挑战包括多样的研究设计、长期数据不足以及技术障碍。未来的研究必须包括标准化的认知评估、纵向调查以及解决数字鸿沟的举措。
