低位前切除综合征（LARS）对直肠癌幸存者生活质量的影响：一项叙述性综述
The impact of Low-Anterior Resection Syndrome (LARS) on the Quality of Life in Rectal Cancer Survivors: a Narrative Review.
作者信息
Stanculea Floris, Ungureanu Claudiu-Octavian, Roca Daniela, Ginghina Octav, Mihailov Raul, Grama Florin, Iordache Niculae
机构信息
"Carol Davila" University of Medicine and Pharmacy, 37 Dionisie Lupu Street, 020021 Bucharest, Romania.
General Surgery Department, "Sf. Ioan" Clinical Emergency Hospital, 13 Vitan-Bârzeşti Road, 042122 Bucharest, Romania.
出版信息
Maedica (Bucur). 2025 Mar;20(1):56-64. doi: 10.26574/maedica.2025.20.1.56.
Abstract
Low anterior rectal cancer is based on oncological radicality and recurrence rates, which translate to survival. Rectal dysfunction occurred in at least one-quarter of patients. This dysfunction is a myriad of symptoms referred to as low anterior resection syndrome (LARS). In this review, we analyzed the definitions, risk factors and pathophysiological mechanisms of LARS. A better understanding of this syndrome can lead to improved prevention and treatment of LARS.
摘要
低位直肠癌基于肿瘤根治性和复发率，而这两者又与生存率相关。至少四分之一的患者出现直肠功能障碍。这种功能障碍是一系列被称为低位前切除综合征（LARS）的症状。在本综述中，我们分析了LARS的定义、危险因素和病理生理机制。对该综合征的更好理解可改善LARS的预防和治疗。
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