Konstantinidis Christos, Konstantinou Alkisti, Plakoutsis Sotiris, Kotsias Christos, Panagiotopoulos Vasileios, Koukos Christos, Anagnostou Evangelos, Pakos Emilios E, Vardakas Dimitrios, Giotis Dimitrios
Orthopaedic Department, General Hospital of Ioannina "G. Hatzikosta", Ioannina, Greece.
Sports Trauma and Pain Institute, Thessaloniki, Greece.
Maedica (Bucur). 2025 Mar;20(1):132-136. doi: 10.26574/maedica.2025.20.1.132.
Giant cell tumors of the synovial membrane are benign but locally aggressive lesions that primarily affect synovial joints. Histologically, they are characterized by the proliferation of histiocytes, multinucleated giant cells and prominent hemosiderin deposition. Clinically, patients often experience joint pain, swelling and restricted movement, which can significantly impact their mobility and quality of life. Traditionally, open surgical excision has been the standard approach for managing these tumors. However, advancements in minimally invasive techniques, particularly arthroscopic surgery, have emerged as effective alternatives. Arthroscopy offers several benefits, including reduced postoperative pain, quicker recovery and minimal surgical trauma, while still allowing for complete tumor removal. This article presents a case of a giant cell tumor of the synovial membrane in the knee of a female patient, highlighting the successful use of arthroscopic treatment and the favorable postoperative outcomes. By presenting this case, we aim to emphasize the growing role of arthroscopic intervention in managing these tumors, further supporting its integration into clinical practice.
滑膜巨细胞瘤是良性但具有局部侵袭性的病变，主要累及滑膜关节。在组织学上，其特征为组织细胞、多核巨细胞的增殖以及显著的含铁血黄素沉积。临床上，患者常出现关节疼痛、肿胀及活动受限，这会显著影响其活动能力和生活质量。传统上，开放手术切除一直是治疗这些肿瘤的标准方法。然而，微创技术的进步，尤其是关节镜手术，已成为有效的替代方法。关节镜手术有诸多益处，包括术后疼痛减轻、恢复更快以及手术创伤最小，同时仍能实现肿瘤的完整切除。本文介绍了一名女性患者膝关节滑膜巨细胞瘤的病例，突出了关节镜治疗的成功应用及良好的术后效果。通过展示该病例，我们旨在强调关节镜干预在治疗这些肿瘤中日益重要的作用，进一步支持其融入临床实践。
