Gudmand-Høyer E
J Pediatr Gastroenterol Nutr. 1985 Dec;4(6):873-7. doi: 10.1097/00005176-198512000-00005.
Thirty-one children with sucrose malabsorption are reported. All had a flat blood sugar curve after sucrose ingestion but a normal one after monosaccharides. Seventy-five percent were malnourished and 11 were dehydrated at admission to hospital. Seven had to have intravenous rehydration. After institution of a sucrose-free diet, the symptoms disappeared and the patients gained weight. Eighteen had had symptoms for greater than 1 year, 13 for greater than 2 years, and 7 for greater than 5 years before their cause was discovered. Familial occurrence of sucrose malabsorption was shown in three to five cases. Four children were reinvestigated 7-15 years after diagnosis. All had chronic dyspepsia, and none kept a strictly sucrose-free diet. Three of the four patients were underweight for their age by from 5 to 16 kg, whereas the fourth was as underweight as compared to height. It is concluded that the high incidence of sucrose malabsorption found in Greenland together with the high sucrose consumption might be of nutritional hygienic significance for the population.
本文报告了31例蔗糖吸收不良的儿童。所有患儿摄入蔗糖后血糖曲线均呈平坦状，但摄入单糖后血糖曲线正常。75%的患儿入院时营养不良，11例存在脱水。7例患儿需要静脉补液。采用无蔗糖饮食后，症状消失，患儿体重增加。18例患儿在病因被发现前症状已持续超过1年，13例超过2年，7例超过5年。3至5例显示有蔗糖吸收不良的家族发病情况。4名儿童在诊断后7至15年接受了复查。所有患儿均有慢性消化不良，且无一严格遵循无蔗糖饮食。4例患者中有3例年龄别体重低于正常5至16千克，而第4例身高别体重也低于正常。研究得出结论，格陵兰岛发现的蔗糖吸收不良高发病率以及高蔗糖消耗量可能对当地人群具有营养卫生学意义。
