Liu Shurong, Zhang Junling, Wang Xin
Department of Gastrointestinal Surgery, Peking University First Hospital, Beijing, China.
Front Oncol. 2025 Jul 3;15:1591475. doi: 10.3389/fonc.2025.1591475. eCollection 2025.
Metastasis of bladder cancer to the stomach was rarely reported before. We reported a case of a 68-year-old woman with metastatic bladder cancer to the stomach. The patient was diagnosed with epithelial cell carcinoma of the bladder and underwent resection of the bladder, the right ureter and right kidney two years ago. One and a half years later, the enhanced CT examination revealed diffuse thickening of the stomach. Gastroscopy showed the gastric mucosa were swollen, congested and stiff. The biopsy of the EUS-FNA (Endoscopic Ultrasound-Guided Fine Needle Aspiration) showed a high likelihood of bladder epithelial tumors. Then the patient underwent a total gastrectomy and immunohistochemistry of the specimen indicated that her tumor tissue was originated from the bladder. We recommend that clinicians remain vigilant for gastric tumors that are metastases from bladder cancer, especially in patients with a previous primary bladder tumor.
膀胱癌转移至胃部此前鲜有报道。我们报告了一例68岁女性发生膀胱癌转移至胃部的病例。该患者两年前被诊断为膀胱上皮细胞癌，并接受了膀胱、右侧输尿管及右肾切除术。一年半后，增强CT检查显示胃部弥漫性增厚。胃镜检查显示胃黏膜肿胀、充血且僵硬。超声内镜引导下细针穿刺活检（EUS-FNA）显示高度疑似膀胱上皮肿瘤。随后患者接受了全胃切除术，标本的免疫组化表明其肿瘤组织起源于膀胱。我们建议临床医生对膀胱癌转移至胃部的肿瘤保持警惕，尤其是既往有原发性膀胱肿瘤的患者。
