Maione Alessio, Calanna Filippo, Napolitano Alessandro, Parmigiani Matteo Davide, Fedele Giuseppe, Menon Alessandra, Compagnoni Riccardo, Ferrua Paolo, Berruto Massimo, Randelli Pietro Simone
U.O.C. 1st Orthopedic Clinic, ASST Gaetano Pini-CTO, Milan, Italy.
Residency Program in Orhopedics and Traumatology, University of Milan, Milan, Italy.
Knee Surg Sports Traumatol Arthrosc. 2025 Sep;33(9):3350-3360. doi: 10.1002/ksa.12793. Epub 2025 Jul 18.
High tibial osteotomy (HTO) can alleviate symptoms and slow osteoarthritis progression in selected patients with arthritic varus knees. However, the role of postoperative joint line obliquity (JLO) in correcting varus deformity remains unclear. The aim of this study was to evaluate clinical and radiological outcomes of HTO-lateral closing-wedge (LCW-HTO) and medial opening-wedge (MOW-HTO)-in treating varus knees with tibial- and femoral-based deformities, considering JLO boundaries (≤4°).
A retrospective analysis was performed on 99 patients (108 knees) with varus knees (preoperative hip-knee-ankle angle [HKA] ≤ 175°) undergoing HTO. Patients were classified into femoral-based (FEM-Var) or tibial-based (TIB-Var) varus groups, regardless of the surgical technique. Radiographs were analysed preoperatively and at the final follow-up (mean, 9 ± 4.2 years; range, 2-18 years). Clinical outcomes were assessed using the Hospital for Special Surgery score, International Knee Documentation Committee score, Tegner score, Numeric Rating Scale, and Crosby-Insall score.
The cohort had a mean age of 49.4 ± 10.2 years (range, 18-64 years) at the time of initial follow up. Sixty-eight knees (63%) underwent LCW-HTO, and 40 (37%) underwent MOW-HTO. The mean HKA improved from 172° ± 4.1° (range, 162°-175°) preoperatively to 178° ± 3° (range, 176°-180°) postoperatively. Most patients achieved a JLO ≤ 4° (TIB-Var: two patients > 4°; FEM-Var: five patients > 4°). The TIB-Var group demonstrated superior JLO correction (mean postoperative JLO: TIB-Var, 2.9° ± 1.5°; FEM-Var, 3.5° ± 1.6°; p < 0.01) and greater changes in the joint line congruency angle (JLCA). Both groups showed significant improvements in all clinical scores (p < 0.01), with no osteoarthritis progression at the last follow-up.
HTO is an effective procedure for treating pathological varus knees, regardless of the site of the deformity. Both FEM-Var and TIB-Var groups showed comparable improvements in the clinical scores, development of osteoarthritis, and the restoration of a neutral mechanical axis. Notably, the TIB-Var group showed superior correction in JLO and achieved better postoperative JLCA than the FEM-Var ones.
Level IV, cohort study.
高位胫骨截骨术(HTO)可缓解症状,并减缓特定膝关节炎内翻患者骨关节炎的进展。然而,术后关节线倾斜度(JLO)在纠正内翻畸形中的作用仍不明确。本研究的目的是评估外侧闭合楔形截骨(LCW-HTO)和内侧开放楔形截骨(MOW-HTO)治疗基于胫骨和股骨畸形的内翻膝的临床和放射学结果,并考虑JLO界限(≤4°)。
对99例(108膝)接受HTO的内翻膝患者(术前髋-膝-踝角[HKA]≤175°)进行回顾性分析。无论手术技术如何,患者被分为基于股骨的(FEM-Var)或基于胫骨的(TIB-Var)内翻组。在术前和最终随访时(平均9±4.2年;范围2-18年)分析X线片。使用特种外科医院评分、国际膝关节文献委员会评分、Tegner评分、数字评定量表和Crosby-Insall评分评估临床结果。
在初次随访时,该队列的平均年龄为49.4±10.2岁(范围18-64岁)。68膝(63%)接受了LCW-HTO,40膝(37%)接受了MOW-HTO。平均HKA从术前的172°±4.1°(范围162°-175°)改善至术后的178°±3°(范围176°-180°)。大多数患者的JLO≤4°(TIB-Var组:2例>4°;FEM-Var组:5例>4°)。TIB-Var组在JLO矫正方面表现更优(术后平均JLO:TIB-Var组为2.9°±1.5°;FEM-Var组为3.5°±1.6°;p<0.01),并且关节线一致性角(JLCA)变化更大。两组在所有临床评分上均有显著改善(p<0.01),在最后一次随访时无骨关节炎进展。
HTO是治疗病理性内翻膝的有效方法,无论畸形部位如何。FEM-Var组和TIB-Var组在临床评分、骨关节炎发展以及中立机械轴恢复方面均有相似的改善。值得注意的是,TIB-Var组在JLO矫正方面表现更优,术后JLCA优于FEM-Var组。
IV级,队列研究。