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内镜下球囊扩张术与腹腔镜输尿管再植术治疗原发性梗阻性巨输尿管的对比研究

A comparative study of endoscopic balloon dilatation and laparoscopic ureteral replantation in the treatment of primary obstructive megaureter.

作者信息

Wang Yan-Xi, Chen Hong-Song, Zhang Zhi-Cheng, Luo Jin, Wang Chong, He Xue-Yu, Liu Zhen-Min, He Da-Wei, Liu Xing, Wei Guang-Hui

机构信息

Department of Urology, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Children's Hospital of Chongqing Medical University, 136 Zhongshan Road, 400014, Chongqing, People's Republic of China.

Ministry of Education Key Laboratory of Child Development and Disorders, National Clinical Research Center for Child Health and Disorders, China International Science and Technology Cooperation Base of Child Development and Critical Disorders, 400014, Chongqing, People's Republic of China.

出版信息

Pediatr Surg Int. 2025 Jul 18;41(1):219. doi: 10.1007/s00383-025-06115-6.

Abstract

PURPOSE

Surgical intervention may be required in some children with primary obstructive megaureter (POM) and laparoscopic ureteral reimplantation (LUR) is regarded as the standard approach. With the recent development of endoscopic technology, endoscopic balloon dilation (EBD) has gained popularity. We sought to describe our initial experience with EBD in treating POM, and to compare efficiency and safety with the LUR.

METHODS

A retrospective chart review was performed on children who underwent EBD or LUR between January 2019 and July 2021. Patient demographics, clinical manifestation and perioperative parameters, complications and primary outcomes were analyzed.

RESULTS

A total of 6 patients underwent EBD and 13 underwent LUR during the study period. There were no significant differences in the demographics, clinical manifestation and pre-operative renal function between the EBD and the LUR groups. Although the EBD series was associated with shorter operative time (p < 0.001), less blood loss (p < 0.001), and shorter postoperative hospitalization (p < 0.001), patients undergoing LUR had a higher success rate (p < 0.01).

CONCLUSIONS

Our preliminary results suggested that the EBD, though more non-invasive, seems less effective in the surgical management of POM. The "one size fits all" approach of EBD does not work with POM. Perhaps the EBD is not effective for all children with POM, but for some specific subtypes. Further studies were needed to better clarify the optimal indications of EBD.

摘要

目的

一些原发性梗阻性巨输尿管(POM)患儿可能需要手术干预,腹腔镜输尿管再植术(LUR)被视为标准方法。随着内镜技术的最新发展,内镜球囊扩张术(EBD)越来越受欢迎。我们试图描述我们在EBD治疗POM方面的初步经验,并将其与LUR的效率和安全性进行比较。

方法

对2019年1月至2021年7月期间接受EBD或LUR治疗的儿童进行回顾性病历审查。分析患者的人口统计学特征、临床表现和围手术期参数、并发症及主要结局。

结果

在研究期间,共有6例患者接受了EBD治疗,13例接受了LUR治疗。EBD组和LUR组在人口统计学特征、临床表现和术前肾功能方面无显著差异。虽然EBD组手术时间较短(p<0.001)、失血量较少(p<0.001)、术后住院时间较短(p<0.001),但接受LUR治疗的患者成功率较高(p<0.01)。

结论

我们的初步结果表明,EBD虽然创伤较小,但在POM的手术治疗中似乎效果较差。EBD的“一刀切”方法不适用于POM。也许EBD并非对所有POM患儿都有效,而是对某些特定亚型有效。需要进一步研究以更好地明确EBD的最佳适应证。

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