Nakamura Kenichi, Ozono Yoshinori, Hasuike Satoru, Hatada Hiroshi, Uchiyama Naomi, Komaki Yuri, Iwakiri Hisayoshi, Nagata Kenji, Umekita Yoshiko, Aishima Shinichi, Kawakami Hiroshi
Division of Gastroenterology and Hepatology, Department of Internal Medicine, Faculty of Medicine, University of Miyazaki, 5200 Kihara, Kiyotake, Miyazaki, 889-1692, Japan.
Section of Oncopathology and Morphological Pathology, Department of Pathology, Faculty of Medicine, University of Miyazaki, Miyazaki, Japan.
Clin J Gastroenterol. 2025 Jul 18. doi: 10.1007/s12328-025-02180-5.
Patients with decompensated cirrhosis complicated by hepatocellular carcinoma (HCC) or those who have undergone liver transplantation following liver failure after HCC treatment should continue to receive post-transplant surveillance. Any new liver tumor must be carefully evaluated to determine whether it is a recurrence of HCC. Focal nodular hyperplasia (FNH), the second most common benign hepatic tumor, is believed to result from the hyperplastic response of hepatocytes to pre-existing vascular malformation. Here, we report a case of hepatic FNH two years after living-donor liver transplantation in a patient who experienced liver failure following treatment for HCC. Given the rarity of hepatic FNH after liver transplantation, we present this case along with a review of the literature.
失代偿期肝硬化合并肝细胞癌（HCC）的患者，或在HCC治疗后肝衰竭接受肝移植的患者，应继续接受移植后监测。任何新发肝脏肿瘤都必须仔细评估，以确定是否为HCC复发。局灶性结节性增生（FNH）是第二常见的肝脏良性肿瘤，被认为是肝细胞对先前存在的血管畸形的增生反应所致。在此，我们报告一例活体肝移植两年后发生肝脏FNH的病例，该患者在HCC治疗后出现肝衰竭。鉴于肝移植后肝脏FNH罕见，我们报告此病例并复习文献。
