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前交叉韧带重建中保留残端技术:一项系统评价和荟萃分析

Remnant-preserving techniques in anterior cruciate ligament reconstruction: a systematic review and meta-analysis.

作者信息

Chen Chunrong, Zhang Jing, Bei Chaoyong, Xin Linwei

机构信息

Department of Joint and Sports Medicine, The First affiliated Hospital of Guilin Medical University, No.15 Lequn Road, Guilin City, 541001, China.

Clinical Teaching and Training Center, Affiliated Hospital of Guilin Medical University, No.15 Lequn Road, Xiufeng District, Guilin City, 541001, China.

出版信息

BMC Surg. 2025 Jul 19;25(1):304. doi: 10.1186/s12893-025-03034-0.

Abstract

BACKGROUND

Anterior cruciate ligament reconstruction (ACLR) is a widely performed procedure to restore knee function and stability. Remnant-preserving techniques have been proposed to improve postoperative outcomes by retaining the proprioceptive and biological benefits of the ACL remnant. Remnant preservation is hypothesized to enhance graft integration and proprioceptive restoration. This systematic review and meta-analysis aimed to evaluate the surgical and functional outcomes of remnant-preserving ACLR compared to standard ACLR.

METHODS

A systematic search of PubMed, Embase, Web of Science, and the Cochrane Library was conducted on November 6, 2024, adhering to PRISMA guidelines. Eligible studies included randomized controlled trials (RCTs) and cohort studies that compared remnant-preserving ACLR with standard ACLR. Outcomes assessed included functional scores (Lysholm and IKDC), knee stability (KT-1000/2000 measurements), and complication rates. Quality assessment was performed using the Newcastle-Ottawa Scale for cohort studies and the Cochrane Risk of Bias tool for RCTs. Statistical analyses utilized fixed- or random-effects models based on heterogeneity.

RESULTS

The meta-analysis included 10 studies, comprising 6 RCTs and 4 cohort studies. Remnant-preserving ACLR demonstrated significant improvements in Lysholm scores (WMD = 0.85; 95% CI, 0.29-1.42; P < 0.05) and knee stability (RCTs: WMD = -0.45; 95% CI, -0.62 to -0.27; P < 0.01; cohort studies: WMD = -0.42; 95% CI, -0.62 to -0.23; P < 0.01). No significant difference was observed in IKDC scores (WMD = -0.21; 95% CI, -1.68 to 1.26; P > 0.05) or complication rates (RR = 1.16; 95% CI, 0.77-1.76; P > 0.05). Publication bias was not detected.

CONCLUSIONS

Remnant-preserving ACLR provides superior functional outcomes and knee stability compared to standard ACLR without increasing complication rates. These findings support the adoption of remnant-preserving techniques in clinical practice. Further research is needed to assess long-term outcomes and refine patient selection criteria.

摘要

背景

前交叉韧带重建术(ACLR)是一种广泛应用的恢复膝关节功能和稳定性的手术。保留残端技术已被提出,旨在通过保留前交叉韧带残端的本体感觉和生物学益处来改善术后效果。保留残端被认为可以增强移植物整合和本体感觉恢复。本系统评价和荟萃分析旨在评估保留残端的ACLR与标准ACLR相比的手术和功能结果。

方法

2024年11月6日,按照PRISMA指南对PubMed、Embase、Web of Science和Cochrane图书馆进行了系统检索。符合条件的研究包括将保留残端的ACLR与标准ACLR进行比较的随机对照试验(RCT)和队列研究。评估的结果包括功能评分(Lysholm和IKDC)、膝关节稳定性(KT-1000/2000测量)和并发症发生率。使用纽卡斯尔-渥太华量表对队列研究进行质量评估,使用Cochrane偏倚风险工具对RCT进行质量评估。统计分析根据异质性采用固定效应或随机效应模型。

结果

荟萃分析纳入了10项研究,包括6项RCT和4项队列研究。保留残端的ACLR在Lysholm评分(加权均数差[WMD]=0.85;95%可信区间[CI],0.29-1.42;P<0.05)和膝关节稳定性方面有显著改善(RCT:WMD=-0.45;95%CI,-0.62至-0.27;P<0.01;队列研究:WMD=-0.42;95%CI,-0.62至-0.23;P<0.01)。IKDC评分(WMD=-0.21;95%CI,-1.68至1.26;P>0.05)或并发症发生率(风险比[RR]=1.16;95%CI,0.77-1.76;P>0.05)未观察到显著差异。未检测到发表偏倚。

结论

与标准ACLR相比,保留残端的ACLR在不增加并发症发生率的情况下提供了更好的功能结果和膝关节稳定性。这些发现支持在临床实践中采用保留残端技术。需要进一步研究来评估长期结果并完善患者选择标准。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/43b2/12275250/67d51657769d/12893_2025_3034_Fig1_HTML.jpg

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