评估ChatGPT在细胞遗传学报告和解读中的可靠性：对临床应用的影响。
Assessing the reliability of ChatGPT in cytogenetic reporting and interpretation: implications for clinical use.
作者信息
Chebly Alain, Veronese Lauren, Chevret Edith
机构信息
Center Jacques Loiselet for Medical Genetics and Genomics (CGGM), Faculty of Medicine, Saint Joseph University of Beirut (USJ), Beirut, Lebanon.
Université Clermont Auvergne, Unité de Recherche 7453 (CHELTER), Clermont-Ferrand, France.
出版信息
Mol Cytogenet. 2025 Jul 18;18(1):16. doi: 10.1186/s13039-025-00717-4.
Abstract
This study evaluates the accuracy of ChatGPT in generating chromosomal representations (formulas) based on ISCN rules in clinical cytogenetics. While ChatGPT generated correct answers for simple cases, it frequently failed in complex cases. These findings highlight the limitations of current AI tools in accurate clinical cytogenetic reporting, reinforcing the vital role of skilled clinical cytogeneticists for accurate interpretation and reporting.
摘要
本研究评估了ChatGPT在根据临床细胞遗传学中的ISCN规则生成染色体表征（公式）方面的准确性。虽然ChatGPT在简单病例中能给出正确答案，但在复杂病例中常常出错。这些发现凸显了当前人工智能工具在准确的临床细胞遗传学报告方面的局限性，强化了熟练的临床细胞遗传学家在准确解读和报告中的关键作用。
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本文引用的文献
1
ISCN 2024 - An International System for Human Cytogenomic Nomenclature (2024).《国际人类细胞基因组命名系统（2024）》（ISCN 2024）
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Complex karyotypes in hematologic disorders: a 12-year single-center study from Lebanon.血液系统疾病中的复杂核型：来自黎巴嫩的一项为期12年的单中心研究。
Front Oncol. 2024 Oct 24;14:1480793. doi: 10.3389/fonc.2024.1480793. eCollection 2024.
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Cancer cytogenetics in the era of artificial intelligence: shaping the future of chromosome analysis.人工智能时代的癌症细胞遗传学：塑造染色体分析的未来。
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Can ChatGPT understand genetics?ChatGPT能理解遗传学吗？
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Cytogenetics and Cytogenomics Evaluation in Cancer.癌症的细胞遗传学和细胞基因组学评估。
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