Ishida T, Izuo M, Iino Y, Ogawa T, Yokoe T, Kawai T
Gan No Rinsho. 1985 May;Suppl:131-42.
Fourty-two patients with suspected non-palpable cancer of the breast due to microcalcifications detected by mammography were studied. Histologically, carcinoma was found in 17 cases (40.5%) and benign lesions in 25 cases (32 foci) at biopsy or operation. Eight cases of these carcinomas were noninvasive and seven were microinvasive. Axillary metastasis was present in only one case. Sites of calcifications were confined to the area of carcinoma in 12 patients; both within a carcinoma and adjacent benign lesions in 3; only within the adjacent benign diseases in two. The features of microcalcification was not always useful to differentiate accurately the benign from the malignant. Therefore, local excision is essential to ensure histological diagnosis in the non-palpable breast lesions with microcalcification.
对42例因乳腺钼靶检查发现微钙化而怀疑为不可触及性乳腺癌的患者进行了研究。组织学检查发现，活检或手术时17例（40.5%）为癌，25例（32个病灶）为良性病变。这些癌中有8例为非浸润性，7例为微浸润性。仅1例有腋窝转移。12例患者钙化部位局限于癌灶区域；3例位于癌灶内及相邻良性病变内；2例仅位于相邻良性病变内。微钙化的特征并不总是有助于准确区分良性与恶性。因此，对于不可触及的伴有微钙化的乳腺病变，局部切除对于确保组织学诊断至关重要。
