Sultana Jesmin, Pitchik Helen O, Shoab Abul Kasham, Huda Tarique Md Nurul, Hasan Rezaul, Akter Fahmida, Jahir Tania, Khobair Hossain Md, Das Jyoti Bhushan, Amin Md Ruhul, Yeasmin Farzana, Khan Rizwana, Forsyth Jenna E, Kwong Laura H, Rashid Jahangir, Ashrafee Sabina, Rahman Mahbubur, Mridha Malay K, Tofail Fahmida, Winch Peter J, Luby Stephen P, Fernald Lia C H
Environmental Health and WASH, Health Systems and Population Studies Division, International Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b), Dhaka, Bangladesh.
Division of Epidemiology, University of California Berkeley School of Public Health, Berkeley, California, USA
BMJ Glob Health. 2025 Jul 20;10(7):e018736. doi: 10.1136/bmjgh-2024-018736.
Small efficacy trials have demonstrated that multicomponent interventions can improve early child development. We evaluated the large-scale delivery of a multicomponent intervention delivered by government health workers throughout a rural subdistrict in northwestern Bangladesh.
We evaluated a group-based, multicomponent intervention with a curriculum covering responsive parenting, caregivers' mental health, lead exposure prevention strategies at the household level, water, sanitation, hygiene and nutrition. Group sessions were held throughout a rural subdistrict of Bangladesh (August 2019-March 2020). A longitudinal sample of caregivers (n=517) of children 6-24 months was assessed at baseline and endline (primary cohort), and 1179 additional caregivers were assessed only at endline (supplementary cross-sectional). Outcomes were the variety of child play activities and materials, number of books, caregiver depressive symptoms and nutrition and lead knowledge. For primary analyses, we used difference-in-difference.
Over half (n=276, 53%) of the cohort participants attended any of the 16 intervention sessions and of these, 83% (228) attended 2+. Caregivers attending 2+ sessions, compared with ≤1 session, had more play materials (adjusted mean difference: 0.58; 95% CI: 0.30, 0.85) and were more likely to have any children's books (adjusted prevalence difference (aPD): 0.26; 95% CI: 0.18, 0.34), to have heard of lead (aPD: 0.13; 95% CI: 0.07, 0.19) or to know how to avoid harm from lead (unadjusted PD: 0.13; 95% CI: 0.08, 0.17). These findings were similar to those from the supplementary cross-sectional analysis. There were no differences in caregiver depressive symptoms in either analysis. More child play activities and nutrition knowledge were associated with attendance in the cross-sectional sample.
A multicomponent child development intervention delivered by government health workers increased the presence of children's toys and books and caregiver knowledge of lead in families who attended two or more sessions. Further adaptation and alternative delivery methods are likely to improve the reach and the breadth of impacts.
NCT04111016.
小型疗效试验表明,多组分干预措施可改善幼儿发育。我们评估了由政府卫生工作者在孟加拉国西北部一个农村分区大规模实施的多组分干预措施。
我们评估了一项基于小组的多组分干预措施,其课程涵盖敏感育儿、照顾者心理健康、家庭层面的铅暴露预防策略、水、环境卫生、个人卫生和营养。小组会议在孟加拉国一个农村分区举行(2019年8月至2020年3月)。对6至24个月儿童的照顾者进行纵向抽样(n = 517),在基线和终点进行评估(主要队列),另外1179名照顾者仅在终点进行评估(补充横断面)。结果包括儿童游戏活动和材料的种类、书籍数量、照顾者的抑郁症状以及营养和铅知识。对于主要分析,我们使用了差分法。
超过一半(n = 276,53%)的队列参与者参加了16次干预会议中的任何一次,其中83%(228人)参加了2次及以上。与参加≤1次会议的照顾者相比,参加2次及以上会议的照顾者有更多的游戏材料(调整后平均差异:0.58;95%置信区间:0.30,0.85),更有可能拥有儿童书籍(调整后患病率差异(aPD):0.26;95%置信区间:0.18,0.34),听说过铅(aPD:0.13;95%置信区间:0.07,0.19)或知道如何避免铅危害(未调整的PD:0.13;95%置信区间:0.08,0.17)。这些发现与补充横断面分析的结果相似。在两项分析中,照顾者的抑郁症状均无差异。在横断面样本中,更多的儿童游戏活动和营养知识与参与度相关。
由政府卫生工作者实施的多组分儿童发育干预措施增加了参加两次或更多次会议的家庭中儿童玩具和书籍的数量以及照顾者对铅的知识。进一步的调整和替代实施方法可能会提高覆盖面和影响范围。
NCT04111016。